Elevated levels of plasma mitochondrial DNA DAMPs are linked to clinical outcome in severely injured human subjects

JD Simmons, YL Lee, S Mulekar, JL Kuck… - Annals of …, 2013 - journals.lww.com
Objective: Our objective was to execute a prospective cohort study to determine
relationships between plasma mtDNA DAMP levels and the occurrence of systemic …

The effect of antioxidant supplementation on bacterial translocation after intestinal ischemia and reperfusion

A Tassopoulos, A Chalkias, A Papalois… - Redox …, 2017 - Taylor & Francis
The intestine is highly sensitive to ischemia/reperfusion (I/R) injury. Intestinal I/R may cause
local tissue injury and disruption of the intestinal mucosal barrier, allowing the passage of …

Reversible myocardial dysfunction in critically ill, noncardiac patients: A review

MR Bailén - Critical care medicine, 2002 - journals.lww.com
Conclusions Reversible myocardial dysfunction may develop in a situation of critical
pathology, but the etiology of reversible myocardial dysfunction is not fully understood. This …

Relationship between oxidative stress in muscle tissue and weight-lifting-induced muscle damage

S Uchiyama, H Tsukamoto, S Yoshimura, T Tamaki - Pflügers Archiv, 2006 - Springer
We examined whether oxidative stress-induced muscle damage occurs during weight-lifting
exercise using the rat model. Male Wistar rats were subjected to a single exhaustive session …

Effect of lung ischemia–reperfusion on oxidative stress parameters of remote tissues

H Esme, H Fidan, T Koken… - European journal of cardio …, 2006 - academic.oup.com
Objective: Ischemia–reperfusion injury induces a systemic inflammatory response and
production of reactive oxygen species, which potentially can be more detrimental than its …

[HTML][HTML] Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury

W Liu, LP Shan, XS Dong, XW Liu, T Ma… - World journal of …, 2013 - ncbi.nlm.nih.gov
AIM: To study the effects of combined early fluid resuscitation and hydrogen inhalation on
septic shock-induced lung and intestine injuries. METHODS: Wistar male rats were …

Attenuation of ischemia/reperfusion injury by N-acetylcysteine in a rat hind limb model

C Koksal, AK Bozkurt, U Cangel, N Ustundag… - Journal of Surgical …, 2003 - Elsevier
Background. Ischemia/reperfusion is a complex set of events with severe pathologic
consequences. Reperfusion initiates both the local and systemic damage in part through …

Resolvin D1 mitigates energy metabolism disorder after ischemia–reperfusion of the rat lung

Q Zhao, J Wu, Q Hua, Z Lin, L Ye, W Zhang… - Journal of translational …, 2016 - Springer
Background Energy metabolism disorder is a critical process in lung ischemia–reperfusion
injury (LIRI). This study was aimed to determine the effects of resolvin D1 (RvD1) on the …

[PDF][PDF] N-acetylcysteine inhibits activation of toll-like receptor 2 and 4 gene expression in the liver and lung after partial hepatic ischemia-reperfusion injury in mice

X Jin, L Wang, HS Wu, L Zhang, CY Wang… - … Pancreat Dis Int, 2007 - researchgate.net
BACKGROUND: Toll-like receptor 2 and 4 (TLR2/4) may play important roles in ischemia-
reperfusion (I/R) injury, and N-acetylcysteine (NAC) can prevent the generation of reactive …

[PDF][PDF] Alteration of renal functional, oxidative stress and inflammatory indices following hepatic ischemia-reperfusion

M Kadkhodaee, S Mikaeili, M Zahmatkesh… - Gen Physiol …, 2012 - academia.edu
Liver ischemia/reperfusion (IR) injury is a complex phenomenon that may cause local as
well as remote organ injuries. Reactive oxygen species (ROS) along with many pro-and anti …