Biological activity of recently discovered halogenated marine natural products

GW Gribble - Marine drugs, 2015 - mdpi.com
This review presents the biological activity—antibacterial, antifungal, anti-parasitic, antiviral,
antitumor, antiinflammatory, antioxidant, and enzymatic activity—of halogenated marine …

Bioactive compounds from marine sponges: Fundamentals and applications

D Varijakzhan, JY Loh, WS Yap, K Yusoff, R Seboussi… - Marine drugs, 2021 - mdpi.com
Marine sponges are sessile invertebrates that can be found in temperate, polar and tropical
regions. They are known to be major contributors of bioactive compounds, which are …

[PDF][PDF] Bioactive natural substances from marine sponges: new developments and prospects for future pharmaceuticals

S Perdicaris, T Vlachogianni… - Nat. Prod. Chem …, 2013 - pdfs.semanticscholar.org
In the last decades researchers of natural products chemistry focused their research in a
wide variety of bioactive compounds from marine species. Marine sponges (Porifera) have …

Natural and synthetic halogenated amino acids—Structural and bioactive features in antimicrobial peptides and peptidomimetics

M Mardirossian, M Rubini, MFA Adamo, M Scocchi… - Molecules, 2021 - mdpi.com
The 3D structure and surface characteristics of proteins and peptides are crucial for
interactions with receptors or ligands and can be modified to some extent to modulate their …

Naturally Prefabricated Marine Biomaterials: Isolation and Applications of Flat Chitinous 3D Scaffolds from Ianthella labyrinthus (Demospongiae: Verongiida)

M Schubert, B Binnewerg, A Voronkina… - International journal of …, 2019 - mdpi.com
Marine sponges remain representative of a unique source of renewable biological materials.
The demosponges of the family Ianthellidae possess chitin-based skeletons with high …

Naturally Occurring Organohalogen Compounds—A Comprehensive Review

GW Gribble - Naturally Occurring Organohalogen Compounds, 2023 - Springer
The present volume is the third in a trilogy that documents naturally occurring
organohalogen compounds, bringing the total number—from fewer than 25 in 1968—to …

Antiparasitic Activity of Bromotyrosine Alkaloids and New Analogues Isolated from the Fijian Marine Sponge Aplysinella rhax

ET Oluwabusola, JN Tabudravu… - Chemistry & …, 2020 - Wiley Online Library
Ten bromotyrosine alkaloids were isolated and characterised from the marine sponge
Aplysinella rhax (de Laubenfels 1954) collected from the Fiji Islands, which included one …

Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics

EI Parkinson, JH Tryon, AW Goering, KS Ju… - ACS chemical …, 2018 - ACS Publications
Natural products (NPs) are a rich source of medicines, but traditional discovery methods are
often unsuccessful due to high rates of rediscovery. Genetic approaches for NP discovery …

Marine Bromotyrosine Derivatives in Spotlight: Bringing Discoveries and Biological Significance

P Ferreira Montenegro, GN Pham, FM Abdoul-Latif… - Marine Drugs, 2024 - mdpi.com
The Verongida order comprises several sponge families, such as Aplysinellidae,
Aplysinidae, Ianthellidae, and Pseudoceratinidae, reported for producing bromotyrosine …

Quorum Sensing Inhibitory and Antifouling Activities of New Bromotyrosine Metabolites from the Polynesian Sponge Pseudoceratina n. sp.

F Tintillier, C Moriou, S Petek, M Fauchon, C Hellio… - Marine drugs, 2020 - mdpi.com
Four new brominated tyrosine metabolites, aplyzanzines C–F (1–4), were isolated from the
French Polynesian sponge Pseudoceratina n. sp., along with the two known 2 …