The flagellum and the injectisome are two of the most complex and fascinating bacterial
nanomachines. At their core, they share a type III secretion system (T3SS), a transmembrane …

In the emerging field of active and specific cancer immunotherapy, strategies using live-
attenuated bacterial vectors have matured in terms of academic and industrial development …

Type III protein secretion systems are being considered for vaccine development as virtually
any protein antigen can be engineered for delivery by these nanomachines into the class I …

The anti-inflammatory cytokine interleukin-10 and its viral homologs were chosen as model
proteins for the development of drug delivery systems based on probiotic carriers like E. coli …

Salmonella is a primary cause of enteric diseases in a variety of animals. During its
evolution into a pathogenic bacterium, Salmonella acquired an elaborate regulatory network …

Active immunotherapy based on live attenuated bacterial vectors has matured in terms of
industrial development and develops through a combination of three phenomena. First …

The type III secretion system (T3SS) of gram-negative bacteria involves dedicated protein
translocation machinery that directly injects proteins into target cells. Pathogenic bacteria …

The main concern of gene therapy is to target the gene of interest to intended cell tissues for
optimizing treatment efficiency. Genetically engineered bacteria have been developed as …

Salmonella enterica subspecies enterica serovar Enteritidis (S. Enteritidis) has been
identified as a significant cause of salmonellosis in humans. Salmonella pathogenicity …

Hace más de cien años en Japón, fue descubierto el bacilo Shiga posteriormente
denominado como S. dysenteriae tipo 1, la shigelosis (denominada así la enfermedad …