Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Recent updates on multifunctional nanomaterials as antipathogens in humans and livestock: classification, application, mode of action, and challenges

S Sadiq, I Khan, Z Shen, M Wang, T Xu, S Khan… - Molecules, 2023 - mdpi.com
Pathogens cause infections and millions of deaths globally, while antipathogens are drugs
or treatments designed to combat them. To date, multifunctional nanomaterials (NMs), such …

A recent update on therapeutic potential of vesicular system against fungal keratitis

SN Sanap, A Kedar, AC Bisen, S Agrawal… - Journal of Drug Delivery …, 2022 - Elsevier
Fungal keratitis (FK) is a highly invasive and challenging corneal infection that can be
deadly if not treated well. Aspergillus, Fusarium, and Candida are the most common …

Update on fungal keratitis

P Garg, A Roy, S Roy - Current opinion in ophthalmology, 2016 - journals.lww.com
Update on fungal keratitis : Current Opinion in Ophthalmology Update on fungal keratitis :
Current Opinion in Ophthalmology Log in or Register Subscribe to journalSubscribe Get new …

A review on ocular novel drug delivery systems of antifungal drugs: functional evaluation and comparison of conventional and novel dosage forms

S Mehrandish, S Mirzaeei - Advanced Pharmaceutical Bulletin, 2020 - pmc.ncbi.nlm.nih.gov
Ocular fungal infections affect more than one million people annually worldwide. They can
lead to impaired vision or even complete blindness, so they should be treated immediately …

Enhanced Killing and Antibiofilm Activity of Encapsulated Cinnamaldehyde against Candida albicans

SN Khan, S Khan, J Iqbal, R Khan… - Frontiers in microbiology, 2017 - frontiersin.org
Candida sp. impelled opportunistic infection in immune-compromised patients ensuing from
asymptomatic colonization to pathogenic forms. Moreover, slow spread of Candida species …

Itraconazole lipid nanocapsules gel for dermatological applications: In vitro characteristics and treatment of induced cutaneous candidiasis

NA El-Sheridy, AA Ramadan, AA Eid… - Colloids and Surfaces B …, 2019 - Elsevier
There is a growing clinical demand for topical itraconazole (ITC) delivery systems because
of the expanding potential of the drug for topical fungal and non-fungal applications. Lipid …

[HTML][HTML] Review of clinical and basic approaches of fungal keratitis

J Wu, WS Zhang, J Zhao, HY Zhou - International journal of …, 2016 - ncbi.nlm.nih.gov
Fungal keratitis (FK) is a serious disease which can cause blindness. This review has
current information about the pathogenesis, limitations of traditional diagnosis and …

Development, characterization and preclinical evaluation of nanosized liposomes of itraconazole for topical application: 32 full factorial design to estimate the …

N Kumar, S Goindi - Journal of Drug Delivery Science and Technology, 2021 - Elsevier
The objective of the study was to statistically develop a novel formulation of itraconazole
(ITZ) loaded nanosized liposomes (NLPs) for effective topical delivery against superficial …

Formulation and evaluation of itraconazole liposomes for Hedgehog pathway inhibition

JR Pace, R Jog, DJ Burgess… - Journal of liposome …, 2020 - Taylor & Francis
Itraconazole (ITZ) is an FDA-approved antifungal agent that has recently been explored for
novel biological properties. In particular, ITZ was identified as a potent inhibitor of the …