The comet assay is a sensitive and rapid method for DNA strand break detection in
individual cells. Its use has increased significantly in the past few years. This paper is a …

Abstract Hydrogen peroxide (H 2 O 2) is a powerful oxidising agent. It gives rise to agents
known to be effective bleaching agents. The mechanisms of bleaching involve the …

The single cell gel electrophoresis or Comet assay is a sensitive, reliable, and rapid method
for DNA double-and single-strand breaks, alkali-labile sites and delayed repair site …

Arsenite, the trivalent form of arsenic present in the environment, is a known human
carcinogen that lacked mutagenic activity in bacterial and standard mammalian cell mutation …

Metal ions can bind to DNA directly or indirectly through hydrogen bonding of the
coordinating water molecules surrounding the metal ions. Metal binding to the bases usually …

This paper is an attempt to initiate a discussion about the causes of radiation-induced
mutagenesis. It considers the evidence for the involvement of singly base-damaged sites as …

Male weanling Fischer 344 rats were fed either a semipurified diet deficient in the methyl
donors methionine, choline, and folic acid or a supplemented control diet for a period of 9 …

The correlation of oxidative stress on development and DNA damage in bovine embryos
was investigated by the comet assay (single-cell microgel electrophoresis), an effective …

Isolated mussel (Mytilus edulisL.) digestive gland cells were analyzed using the single-cell
gel electrophoresis or “comet” assay to assess the ability of potential aquatic contaminants …

Comet assay under neutral conditions allows the detection of DNA double-strand breaks
(DSB), considered to be the biologically relevant radiation-induced lesion. In this report, we …