Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Today's biologics manufacturing practices incur high costs to the drug makers, which can
contribute to high prices for patients. Timely investment in the development and …

Membrane systems play an essential role in the production of all biopharmaceuticals. This
includes initial clarification of cell culture fluid by both depth filtration and tangential flow …

There is a growing application of integrated and continuous bioprocessing (ICB) for
manufacturing recombinant protein therapeutics produced from mammalian cells. At first …

Purpose There is a growing interest in continuous biopharmaceutical processing due to the
advantages of small footprint, increased productivity, consistent product quality, high …

The significant increase in product titers, coupled with the growing focus on continuous
bioprocessing, has renewed interest in using precipitation as a low‐cost alternative to …

There is renewed interest in the possibility of using precipitation for initial capture of high‐
value therapeutic proteins as part of an integrated continuous downstream process …

Continuous precipitation is a new unit operation for the continuous capture of antibodies.
The capture step is based on continuous precipitation with PEG6000 and Zn++ in a tubular …

The concept of continuous manufacturing has gained significant interest from the
biopharmaceutical industry over the past several years. Benefits include increased …

The biopharmaceutical industry has an ongoing interest in improving manufacturing
efficiency and productivity while at the same time reducing manufacturing costs by …