Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …

Among inorganic materials, divalent cations modulate thousands of physiological processes
that support life. Their roles in protein assembly and aggregation are less known, although …

Dark days for diabetic patients were transformed into an era of hope when the therapeutic
usage of insulin was discovered. However, those initial glory days changed to being …

Among bio-inspired protein materials, secretory protein microparticles are of clinical interest
as self-contained, slow protein delivery platforms that mimic secretory granules of the human …

Bacterial inclusion bodies (IBs) are mechanically stable protein particles in the microscale,
which behave as robust, slow‐protein‐releasing amyloids. Upon exposure to cultured cells …

Functional amyloids produced in bacteria as nanoscale inclusion bodies are intriguing but
poorly explored protein materials with wide therapeutic potential. Since they release …

Proteins are biological macromolecules involved in a wide range of biological functions,
which makes them very appealing as therapeutics agents. Indeed, compared to small …

Two structurally and functionally unrelated proteins, namely Omomyc and p31, are
engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria. In this …

Advanced medical treatments involving drug delivery require fully biocompatible materials
with the ability to release functional drugs in a time‐prolonged way. Ideally, the delivered …

Lysosomal storage disorders (LSDs) are a group of rare diseases in which the defect of a
lysosomal protein results in a pathogenic accumulation of nonmetabolized products within …