Genomics of disease risk in globally diverse populations

D Gurdasani, I Barroso, E Zeggini… - Nature Reviews …, 2019 - nature.com
Risk of disease is multifactorial and can be shaped by socio-economic, demographic,
cultural, environmental and genetic factors. Our understanding of the genetic determinants …

The genetic and environmental factors for keratoconus

A Gordon-Shaag, M Millodot… - BioMed research …, 2015 - Wiley Online Library
Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone‐
shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It …

Consanguinity, human evolution, and complex diseases

AH Bittles, ML Black - … of the National Academy of Sciences, 2010 - National Acad Sciences
There is little information on inbreeding during the critical early years of human existence.
However, given the small founding group sizes and restricted mate choices it seems …

[图书][B] Psychologie der Beziehung

J Asendorpf, R Banse, FJ Neyer - 2017 - books.google.com
Kann man Liebe und Konflikte in Partnerschaften–oder die Sicherheit, die eine Mutter ihrem
Kind spendet–wissenschaftlich untersuchen, ja sogar messen? Wie verändern sich …

A review of the reproductive consequences of consanguinity

O Oniya, K Neves, B Ahmed, JC Konje - European Journal of Obstetrics & …, 2019 - Elsevier
Background Consanguinity is the close union, sexual relationship or marriage between
persons who have common biological ancestors usually up to about 2nd cousins. Contrary …

Genetics of consanguinity and inbreeding in health and disease

M Fareed, M Afzal - Annals of human biology, 2017 - Taylor & Francis
Context: Inbreeding increases the level of homozygotes for autosomal recessive disorders
and is the major objective in clinical studies. The prevalence of consanguinity and the …

Is consanguinity a risk factor for keratoconus?

A Gordon-Shaag, M Millodot, M Essa… - Optometry and Vision …, 2013 - journals.lww.com
Methods A questionnaire was distributed to all patients presenting to St. John Eye Hospital,
Jerusalem, Israel. Questionnaire included data on demographic characteristics and potential …

[图书][B] Women and the Making of the Mongol Empire

AF Broadbridge - 2018 - books.google.com
How did women contribute to the rise of the Mongol Empire while Mongol men were
conquering Eurasia? This book positions women in their rightful place in the otherwise well …

Consanguinity and inbreeding in health and disease in North African populations

L Romdhane, N Mezzi, Y Hamdi… - Annual review of …, 2019 - annualreviews.org
North Africa is defined as the geographical region separated from the rest of the continent by
the Sahara and from Europe by the Mediterranean Sea. The main demographic features of …

Consanguinity: A blessing or menace at population level?

MA Bhinder, H Sadia, N Mahmood… - Annals of human …, 2019 - Wiley Online Library
Consanguinity has highly complex and multifaceted aspects with sociocultural as well as
biological debates on its pros and cons. The biological upshot of consanguinity includes the …