Surface tissues of the body such as the skin and intestinal tract are in direct contact with the
external environment and are thus continuously exposed to large numbers of …

Almost 90 years have passed since Alexander Fleming discovered the antimicrobial activity
of lysozyme, the first natural antibiotic isolated from our body. Since then, various types of …

American tegumentary leishmaniasis is a vector-borne parasitic disease caused by
Leishmania protozoans. Innate immune cells undergo long-term functional reprogramming …

Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …

Antimicrobial peptides from a wide spectrum of insects possess potent microbicidal
properties against microbial-related diseases. In this study, seven new gene fragments of …

Introduction: Parasitic diseases that pose a threat to human life include leishmaniasis–
caused by protozoan parasite Leishmania species. Existing drugs have limitations due to …

Objective: The aim of this review is to examine the multiple activities of antimicrobial
peptides (AMPs) in vertebrates. Content: The largest AMP families are the cathelicidins and …

Background CNV comprises a large proportion in cattle genome and is associated with
various traits. However, there were few population-scale comparison studies on cattle CNV …

Phospholipase A 2 toxins present in snake venoms interact with biological membranes and
serve as structural models for the design of small peptides with anticancer, antibacterial and …