Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …

This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Inflammation is a protective response of the body potentially caused by microbial, viral, or
fungal infections, tissue damage, or even autoimmune reactions. The cardinal signs of …

One in every three deaths worldwide is caused by cardiovascular diseases (CVDs),
estimating a total of 17.9 million deaths annually. By 2030, it is expected that more than 24 …

Diabetes mellitus (DM) and its associated complications are considered one of the major
health risks globally. Among numerous complications, diabetic cardiomyopathy (DCM) is …

Acetaminophen (APAP) is one of the most widely used drugs in the world. The literature
shows that excessive or long-term use of APAP can lead to increased cardiovascular …

A growing body of literature has attempted to characterize how traffic-related air pollution
(TRAP) affects molecular and subclinical biological processes in ways that could lead to …

Chronic hyperglycemia initiates multiple pathways that contribute to developing
complications in individuals with diabetes, ultimately leading to significant health problems …

Diabetic neuropathy (DN) is a neurodegenerative disorder that is primarily characterized by
distal sensory loss, reduced mobility, and foot ulcers that may potentially lead to amputation …

Gastrointestinal (GI) complications, including diarrhea, constipation, and gastroparesis, are
common in patients with diabetes. Dysregulation of the Na+/H+ exchanger NHE3 in the …