Recent development of gold (I) and gold (III) complexes as therapeutic agents for cancer diseases

Y Lu, X Ma, X Chang, Z Liang, L Lv, M Shan… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

Highly Enantio‐and Diastereoselective Hydrogenation of Cyclic Tetra‐Substituted β‐Enamido Phosphorus Derivatives

JH Zhang, H Xu, X Tang, Y Dang… - Angewandte Chemie …, 2023 - Wiley Online Library
Catalytic asymmetric hydrogenation of enamido phosphorus derivatives is one of the most
efficient methods for the construction of chiral amino phosphorus products, among which the …

Photoredox-catalyzed C(sp3)─H radical functionalization to enable asymmetric synthesis of α-chiral alkyl phosphine

Z Tan, Y Liu, X Feng - Science Advances, 2024 - science.org
α-Chiral alkyl phosphines are privileged structural motifs with a wide application in organic
and medical synthesis. It is highly desirable to develop stereoselective methods to prepare …

Design, synthesis, and preclinical activity in ovarian cancer models of new phosphanegold (I)-N-heterocyclic carbene complexes

AAA Sulaiman, N Casagrande… - Journal of Medicinal …, 2022 - ACS Publications
A new series of seven gold (I) complexes (1–7) containing 1, 3-bis (2, 6-diisopropylphenyl)
imidazol-2-ylidene (IPr) and phosphane ligands (L1–L7) were synthesized and evaluated …

A novel cyclic dinuclear gold (I) complex induces anticancer activity via an oxidative stress-mediated intrinsic apoptotic pathway in MDA-MB-231 cancer cells

AK Abogosh, MK Alghanem, S Ahmad… - Dalton …, 2022 - pubs.rsc.org
A new dinuclear cyclic gold (I) complex [Au2 (DCyPA) 2](PF6) 2, 1, based on bis [2-(
dicyclohexylphosphano) ethyl] amine (DCyPA) has been synthesized and characterized by …

Novel dinuclear gold (I) complexes containing bis (diphenylphosphano) alkanes and (biphenyl-2-yl)(di-tert-butyl) phosphane: synthesis, structural characterization …

AAA Sulaiman, S Ahmad, SM Hashimi… - New Journal of …, 2022 - pubs.rsc.org
Four novel dinuclear phosphanegold (I) complexes containing bis (diphenylphosphano)
alkanes and (biphenyl-2-yl) di-tert-butylphosphane (Bdbp),[Au2 (Bdbp) 2 (Dppe)](PF6) 2 …

Dinuclear gold (I) complexes based on carbene and diphosphane ligands: bis [2-(dicyclohexylphosphano) ethyl] amine complex inhibits the proteasome activity …

N Casagrande, C Borghese, G Corona… - JBIC Journal of …, 2023 - Springer
Three new dinuclear gold (I) complexes (1–3) containing a carbene (1, 3-Bis (2, 6-di-
isopropylphenyl) imidazol-2-ylidene (IPr)) and diphosphane ligands [bis (1, 2 …

Synthesis, characterization, DFT optimization and anticancer evaluation of phosphanegold (I) dithiocarbamates

AA Sulaiman, W Zierkiewicz, M Michalczyk… - Journal of Molecular …, 2020 - Elsevier
Six phosphanegold (I)-dithiocarbamate complexes (1–6) of general formula [Au (L)(S 2 CNR
2)](where L= 2-(di-isopropylphosphanyl)-1-aminoethane (AEP) and 3-(di …

Synthesis, anticancer activity and apoptosis induction of gold (I) complexes containing tris (o-methoxyphenyl) phosphane

AAA Sulaiman, A Alhoshani, S Ahmad… - Inorganica Chimica …, 2021 - Elsevier
Four new phosphanegold (I) complexes;[Au {(o-MeO-Ph) 3 P} Cl](1),[Au {(o-MeO-Ph) 3
P}{(Me-Et-Ph) P}] Cl (2),[Au {(o-MeO-Ph) 3 P}(Ph 3 P)] Cl (3) and [Au {(o-MeO-Ph) 3 P} 2] Cl …

Synthesis and structural characterization of new gold (I) complexes as bioactive and antitumor agents

LB De Oliveira, LRV Favarin, VO Araújo, NL Faganello… - Polyhedron, 2022 - Elsevier
New mononuclear gold (I) complexes based on 1-thiocarbamoyl-3, 5-diaryl-pyrazoline
ligands were synthesized and structurally characterized using X-ray crystallography, 13 C …