It is generally acknowledged that reactive oxygen species (ROS) play crucial roles in a
variety of natural processes in cells. If increased to levels which cannot be neutralized by the …

The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function
is undeniable. Evidence indicates that this transcription factor exerts massive regulatory …

Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …

The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …

Virus‐induced oxidative stress plays a critical role in the viral life cycle as well as the
pathogenesis of viral diseases. In response to reactive oxygen species (ROS) generation by …

The transcription factor NRF2 is central to redox homeostasis in animal cells and is a well-
known driver of chemoresistance in many types of cancer. Recently, new roles have been …

The Nuclear factor erythroid2-related factor2 (Nrf2), a master regulator of redox
homoeostasis, is a key transcription factor regulating a wide array of genes for antioxidant …

The nuclear factor erythroid 2 related factor 2 (Nrf2) is a major regulator of intracellular
inducible defense systems against harmful endogenous and exogenous substances in the …

The advent of combined antiretroviral treatment (cART) as a treatment for HIV-1 infection has
not only resulted in a dramatic decrease in the peripheral viral load but has also led to …

In mammalian cells, the content of polyamines is tightly regulated. Polyamines, including
spermine, spermidine and putrescine, are involved in many cellular processes. Spermine …