Abstract Purpose Proton pump inhibitors (PPIs) reduce acid secretion in the stomach and
rank as one of the most widely used acid-suppressing medicines globally. While PPIs are …

Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

Orthostatic hypotension (OH) is an abnormal blood pressure response to standing, which is
associated with an increased risk of adverse outcomes such as syncope, falls, cognitive …

BACKGROUND/OBJECTIVES To examine the prevalence of potentially inappropriate
medication (PIM) prescribing and its association with healthcare utilization and related …

Background Individuals with dementia or mild cognitive impairment frequently have multiple
chronic conditions (defined as≥ 2 chronic medical conditions) and take multiple …

Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …

Aims Community‐based pharmacists are an important stakeholder in providing continuing
care for chronic multi‐morbid patients, and their role is steadily expanding. The aim of this …

Older adults commonly end up on many medications. Deprescribing is an important part of
individualizing care for older adults. It is an opportunity to discuss treatment options and …

Importance Older patients using many prescription drugs (hyperpolypharmacy) may be at
increased risk of adverse drug effects. Objective To test the effectiveness and safety of a …