[HTML][HTML] Natural and experimental SARS-CoV-2 infection in domestic and wild animals

DA Meekins, NN Gaudreault, JA Richt - Viruses, 2021 - mdpi.com
SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic,
which continues to spread with devastating effects on global health and socioeconomics …

Molecular aspects concerning the use of the SARS-CoV-2 receptor binding domain as a target for preventive vaccines

Y Valdes-Balbin, D Santana-Mederos… - ACS central …, 2021 - ACS Publications
The development of recombinant COVID-19 vaccines has resulted from scientific progress
made at an unprecedented speed during 2020. The recombinant spike glycoprotein …

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T …

J Pollet, WH Chen, L Versteeg, B Keegan… - Human vaccines & …, 2021 - Taylor & Francis
There is an urgent need for an accessible and low-cost COVID-19 vaccine suitable for low-
and middle-income countries. Here, we report on the development of a SARS-CoV-2 …

[HTML][HTML] Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants

T Li, W Xue, Q Zheng, S Song, C Yang, H Xiong… - Nature …, 2021 - nature.com
The emergence of numerous variants of SARS-CoV-2, the causative agent of COVID-19,
has presented new challenges to the global efforts to control the COVID-19 pandemic. Here …

Affinity exploration of SARS-CoV-2 RBD variants to mAb-functionalized plasmonic metasurfaces for label-free immunoassay boosting

F Li, J Hong, C Guan, K Chen, Y Xie, Q Wu, J Chen… - ACS …, 2023 - ACS Publications
Plasmonic metasurfaces (PMs) functionalized with the monoclonal antibody (mAb) are
promising biophotonic sensors for biomolecular interaction analysis and convenient …

Development of variant‐proof severe acute respiratory syndrome coronavirus 2, pan‐sarbecovirus, and pan‐β‐coronavirus vaccines

J Zhou, Z Liu, G Zhang, W Xu, L Xing… - Journal of Medical …, 2023 - Wiley Online Library
The newly emerged severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
variants with high transmission rates and striking immune evasion have posed a serious …

[HTML][HTML] Principles of SARS-CoV-2 glycosylation

H Chawla, E Fadda, M Crispin - Current Opinion in Structural Biology, 2022 - Elsevier
The structure and post-translational processing of the SARS-CoV-2 spike glycoprotein (S) is
intimately associated with the function of the virus and of sterilising vaccines. The surface of …

[HTML][HTML] Comparative immunogenicity of the recombinant receptor-binding domain of protein S SARS-CoV-2 obtained in prokaryotic and mammalian expression …

IA Merkuleva, DN Shcherbakov, MB Borgoyakova… - Vaccines, 2022 - mdpi.com
The receptor-binding domain (RBD) of the protein S SARS-CoV-2 is considered to be one of
the appealing targets for developing a vaccine against COVID-19. The choice of an …

[HTML][HTML] Safety, tolerability, and immunogenicity of COVID-19 vaccines: a systematic review and meta-analysis

P Yuan, P Ai, Y Liu, Z Ai, Y Wang, W Cao, X Xia… - MedRxiv, 2020 - ncbi.nlm.nih.gov
We aimed to summarize reliable medical evidence by the meta-analysis of all published
clinical trials that investigated the safety, tolerability, and immunogenicity of vaccine …

Nanotechnology and COVID-19 convergence: toward new planetary health interventions against the pandemic

P Sahoo, J Dey, SR Mahapatra, A Ghosh… - OMICS: A Journal of …, 2022 - liebertpub.com
COVID-19 is a systemic disease affecting multiple organ systems and caused by infection
with the SARS-CoV-2 virus. Two years into the COVID-19 pandemic and after the …