Whole-genome sequencing as part of national and international surveillance programmes for antimicrobial resistance: a roadmap

NIHR Global Health Research Unit on Genomic … - BMJ Global …, 2020 - gh.bmj.com
The global spread of antimicrobial resistance (AMR) and lack of novel alternative treatments
have been declared a global public health emergency by WHO. The greatest impact of AMR …

High-throughput sequencing application in the diagnosis and discovery of plant-infecting viruses in Africa, a decade later

JD Ibaba, A Gubba - Plants, 2020 - mdpi.com
High-throughput sequencing (HTS) application in the field of plant virology started in 2009
and has proven very successful for virus discovery and detection of viruses already known …

Expanding research capacity in Sub-Saharan Africa through informatics, bioinformatics, and data science training programs in Mali

JG Shaffer, FJ Mather, M Wele, J Li, CO Tangara… - Frontiers in …, 2019 - frontiersin.org
Bioinformatics and data science research have boundless potential across Africa due to its
high levels of genetic diversity and disproportionate burden of infectious diseases, including …

Whole-exome sequencing reveals uncaptured variation and distinct ancestry in the Southern African population of Botswana

G Retshabile, BC Mlotshwa, L Williams… - The American Journal of …, 2018 - cell.com
Large-scale, population-based genomic studies have provided a context for modern medical
genetics. Among such studies, however, African populations have remained relatively …

Bioinformatics mentorship in a resource limited setting

D Jjingo, G Mboowa, I Sserwadda… - Briefings in …, 2022 - academic.oup.com
Background The two recent simultaneous developments of high-throughput sequencing and
increased computational power have brought bioinformatics to the forefront as an important …

Addressing the shortage of pathologists in Africa: Creation of a MMed Programme in Pathology in Zambia

V Mudenda, E Malyangu, S Sayed… - African Journal of …, 2020 - scielo.org.za
Abstract MUDENDA, Victor; MALYANGU, Evans; SAYED, Shahin and FLEMING, Kenneth.
Addressing the shortage of pathologists in Africa: Creation of a MMed Programme in …

A Review of the Important Weapons against Antimicrobial Resistance in Sub-Saharan Africa

N Gahamanyi, T Umuhoza, SI Saeed, LN Mayigane… - Applied …, 2023 - mdpi.com
Antimicrobial resistance (AMR) is one of the top 10 global health threats facing humanity,
and the sub-Saharan Africa (SSA) is among the heavily affected regions due to its weak …

Parents and provider perspectives on the return of genomic findings for cleft families in Africa

AM Oladayo, S Prochaska, T Busch… - AJOB empirical …, 2024 - Taylor & Francis
Background Inadequate knowledge among health care providers (HCPs) and parents of
affected children limits the understanding and utility of secondary genetic findings (SFs) in …

[HTML][HTML] The emergence of genomic research in Africa and new frameworks for equity in biomedical research

AR Bentley, S Callier, C Rotimi - Ethnicity & disease, 2019 - ncbi.nlm.nih.gov
Individuals with African ancestry have the greatest genomic diversity in the world, yet they
have been underrepresented in genomic research. To advance our understanding of human …

A roadmap for building data science capacity for health discovery and innovation in Africa

J Beyene, SW Harrar, M Altaye, T Astatkie… - Frontiers in Public …, 2021 - frontiersin.org
Technological advances now make it possible to generate diverse, complex and varying
sizes of data in a wide range of applications from business to engineering to medicine. In the …