Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

What Is Known about the Immune Response Induced by Plasmodium vivax Malaria Vaccine Candidates?

C López, Y Yepes-Pérez, N Hincapié-Escobar… - Frontiers in …, 2017 - frontiersin.org
Malaria caused by Plasmodium vivax continues being one of the most important infectious
diseases around the world; P. vivax is the second most prevalent species and has the …

A cost-effectiveness tool for informing policies on Zika virus control

JA Alfaro-Murillo, AS Parpia… - PLoS neglected …, 2016 - journals.plos.org
Background As Zika virus continues to spread, decisions regarding resource allocations to
control the outbreak underscore the need for a tool to weigh policies according to their cost …

New insights into the Plasmodium vivax transcriptome using RNA-Seq

L Zhu, S Mok, M Imwong, A Jaidee, B Russell… - Scientific reports, 2016 - nature.com
Historically seen as a benign disease, it is now becoming clear that Plasmodium vivax can
cause significant morbidity. Effective control strategies targeting P. vivax malaria is hindered …

Rational development of a protective P. vivax vaccine evaluated with transgenic rodent parasite challenge models

AM Salman, E Montoya-Díaz, H West, A Lall… - Scientific reports, 2017 - nature.com
Abstract Development of a protective and broadly-acting vaccine against the most widely
distributed human malaria parasite, Plasmodium vivax, will be a major step towards malaria …

Randomized clinical trial to assess the protective efficacy of a Plasmodium vivax CS synthetic vaccine

M Arévalo-Herrera, X Gaitán, M Larmat-Delgado… - Nature …, 2022 - nature.com
A randomized, double-blind, controlled vaccine clinical trial was conducted to assess, as the
primary outcome, the safety and protective efficacy of the Plasmodium vivax …

In silico Identification and Validation of a Linear and Naturally Immunogenic B-Cell Epitope of the Plasmodium vivax Malaria Vaccine Candidate Merozoite Surface …

RN Rodrigues-da-Silva, JH Martins da Silva, B Singh… - PLoS …, 2016 - journals.plos.org
Synthetic peptide vaccines provide the advantages of safety, stability and low cost. The
success of this approach is highly dependent on efficient epitope identification and synthetic …

[HTML][HTML] Mapping malaria in municipalities of the Coffee Triangle region of Colombia using Geographic Information Systems (GIS)

AJ Rodriguez-Morales, CA Orrego-Acevedo… - Journal of Infection and …, 2015 - Elsevier
Summary Geographical Information Systems (GIS) have been used extensively for the
development of epidemiological maps of malaria but not in the Coffee Triangle region of …

Biological, immunological and functional properties of two novel multi-variant chimeric recombinant proteins of CSP antigens for vaccine development against …

SH Shabani, S Zakeri, AH Salmanian, J Amani… - Molecular …, 2017 - Elsevier
The circumsporozoite protein (CSP) of the malaria parasite Plasmodium vivax is a major pre-
erythrocyte vaccine candidate. The protein has a central repeat region that belongs to one of …

Induction of multifunctional broadly reactive T cell responses by a Plasmodium vivax circumsporozoite protein recombinant chimera

M Cabrera-Mora, JA Fonseca, B Singh… - Infection and …, 2015 - Am Soc Microbiol
Plasmodium vivax is the most widespread species of Plasmodium, causing up to 50% of the
malaria cases occurring outside sub-Saharan Africa. An effective vaccine is essential for …