Lung cancer mutation profile of EGFR, ALK, and KRAS: Meta-analysis and comparison of never and ever smokers

AM Chapman, KY Sun, P Ruestow, DM Cowan… - Lung cancer, 2016 - Elsevier
Lung cancer is the leading cause of cancer-related mortality. While the majority of lung
cancers are associated with tobacco smoke, approximately 10–15% of US lung cancers …

Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers

E Jiagge, DX Jin, JY Newberg, T Perea-Chamblee… - Cancer cell, 2023 - cell.com
Cancer genomes from patients with African (AFR) ancestry have been poorly studied in
clinical research. We leverage two large genomic cohorts to investigate the relationship …

Frequency of brain metastases in non-small-cell lung cancer, and their association with epidermal growth factor receptor mutations

T Iuchi, M Shingyoji, M Itakura, S Yokoi… - International journal of …, 2015 - Springer
Background The brain is a frequent site of metastases from non-small-cell lung cancer
(NSCLC). We analyzed the frequency of brain metastases (BMs) from NSCLC in the era of …

Racial and ethnic differences in the epidemiology and genomics of lung cancer

MB Schabath, WD Cress, T Muñoz-Antonia - Cancer Control, 2016 - journals.sagepub.com
Background Lung cancer is the most common cancer in the world. In addition to the
geographical and sex-specific differences in the incidence, mortality, and survival rates of …

An elevated rate of whole-genome duplications in cancers from Black patients

LM Brown, RA Hagenson, T Koklič, I Urbančič… - Nature …, 2024 - nature.com
Abstract In the United States, Black individuals have higher rates of cancer mortality than
any other racial group. Here, we examine chromosome copy number changes in cancers …

Lung cancer health disparities

BM Ryan - Carcinogenesis, 2018 - academic.oup.com
Compared with all other racial and ethnic groups in the United States, African Americans are
disproportionally affected by lung cancer, both in terms of incidence and survival. It is likely …

Role of sex hormones in lung cancer

N Fuentes, M Silva Rodriguez… - … Biology and Medicine, 2021 - journals.sagepub.com
Lung cancer represents the world's leading cause of cancer deaths. Sex differences in the
incidence and mortality rates for various types of lung cancers have been identified, but the …

Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium

CE Steuer, M Behera, L Berry, S Kim, M Rossi, G Sica… - Cancer, 2016 - Wiley Online Library
BACKGROUND The discovery of oncogenic drivers has ushered in a new era for lung
cancer, but the role of these mutations in different racial/ethnic minorities has been …

Comparison of prevalence and types of mutations in lung cancers among black and white populations

JD Campbell, C Lathan, L Sholl, M Ducar… - JAMA …, 2017 - jamanetwork.com
Importance Lung cancer is the leading cause of cancer death in the United States in all
ethnic and racial groups. The overall death rate from lung cancer is higher in black patients …

A staging auxiliary diagnosis model for nonsmall cell lung cancer based on the intelligent medical system

J Wu, F Gou, Y Tan - Computational and Mathematical Methods …, 2021 - Wiley Online Library
At present, human health is threatened by many diseases, and lung cancer is one of the
most dangerous tumors that threaten human life. In most developing countries, due to the …