We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid derived in
methionine metabolism. The increased level of Hcy in plasma, hyperhomocysteinemia, is …

Identification of modifiable risk factors provides a crucial approach to the prevention of
dementia. Nutritional or nutrient-dependent risk factors are especially important because …

Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

Background Long-term exposure to fine particles (particulate matter≤ 2.5 μm; PM2. 5) has
been consistently linked to heart and lung disease. Recently, there has been increased …

Background Older people suffering from dementia are at increased risk of malnutrition due
to various nutritional problems, and the question arises which interventions are effective in …

The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …

Background Homocysteine is a risk factor for Alzheimer's disease. In the first report on the
VITACOG trial, we showed that homocysteine‐lowering treatment with B vitamins slows the …

Objectives To evaluate the combined action of folic acid and vitamin B12 supplementation
on cognitive performance and inflammation in patients with Alzheimer's disease (AD) …

Behind only Alzheimer's disease, vascular contributions to cognitive impairment and
dementia (VCID) is the second most common cause of dementia, affecting roughly 10–40 …