The biology and evolution of spider venoms
Spiders are diverse, predatory arthropods that have inhabited Earth for around 400 million
years. They are well known for their complex venom systems that are used to overpower …
years. They are well known for their complex venom systems that are used to overpower …
[HTML][HTML] Snake venomics: fundamentals, recent updates, and a look to the next decade
CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
[HTML][HTML] Beyond the 'big four': Venom profiling of the medically important yet neglected Indian snakes reveals disturbing antivenom deficiencies
RRS Laxme, S Khochare, HF de Souza… - PLoS neglected …, 2019 - journals.plos.org
Background Snakebite in India causes the highest annual rates of death (46,000) and
disability (140,000) than any other country. Antivenom is the mainstay treatment of …
disability (140,000) than any other country. Antivenom is the mainstay treatment of …
Convergent evolution of pain-inducing defensive venom components in spitting cobras
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …
change. Snake venoms, with a direct genetic basis and clearly defined functional …
[HTML][HTML] Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by …
Snakebite is a global tropical disease that has long had huge implications for human health
and well-being. Despite its long-standing medical importance, it has been the most …
and well-being. Despite its long-standing medical importance, it has been the most …
The concept of Big Four: Road map from snakebite epidemiology to antivenom efficacy
G Gopal, S Muralidar, D Prakash… - International journal of …, 2023 - Elsevier
Snake envenomation is a life-threatening disease caused by the injection of venom toxins
from the venomous snake bite. Snakebite is often defined as the occupational or domestic …
from the venomous snake bite. Snakebite is often defined as the occupational or domestic …
[HTML][HTML] An in vitro methodology for discovering broadly-neutralizing monoclonal antibodies
Broadly-neutralizing monoclonal antibodies are of high therapeutic utility against infectious
diseases caused by bacteria and viruses, as well as different types of intoxications …
diseases caused by bacteria and viruses, as well as different types of intoxications …
[HTML][HTML] Unveiling the functional epitopes of cobra venom cytotoxin by immunoinformatics and epitope-omic analyses
Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for
the dermonecrotic symptoms of cobra envenomation. However, CTX is generally low in …
the dermonecrotic symptoms of cobra envenomation. However, CTX is generally low in …
[HTML][HTML] A neurotoxic snake venom without phospholipase A2: Proteomics and cross-neutralization of the venom from Senegalese cobra, Naja senegalensis …
The Senegalese cobra, Naja senegalensis, is a non-spitting cobra species newly erected
from the Naja haje complex. Naja senegalensis causes neurotoxic envenomation in …
from the Naja haje complex. Naja senegalensis causes neurotoxic envenomation in …
Elucidating the biogeographical variation of the venom of Naja naja (spectacled cobra) from Pakistan through a venom-decomplexing proteomic study
Naja naja is a medically important species that is distributed widely in South Asia. Its venom
lethality and neutralization profile have been reported to vary markedly, but the …
lethality and neutralization profile have been reported to vary markedly, but the …