[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions

P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …

Mitochondrial dysfunction: roles in skeletal muscle atrophy

X Chen, Y Ji, R Liu, X Zhu, K Wang, X Yang… - Journal of Translational …, 2023 - Springer
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …

Exercise attenuates the major hallmarks of aging

N Garatachea, H Pareja-Galeano… - Rejuvenation …, 2015 - liebertpub.com
Regular exercise has multi-system anti-aging effects. Here we summarize how exercise
impacts the major hallmarks of aging. We propose that, besides searching for novel …

Aging hallmarks: the benefits of physical exercise

A Rebelo-Marques, A De Sousa Lages… - Frontiers in …, 2018 - frontiersin.org
World population has been continuously increasing and progressively aging. Aging is
characterized by a complex and intraindividual process associated with nine major cellular …

[PDF][PDF] lo Buglio

F Bellanti, AD Romano - 2021 - academia.edu
Safety of healthcare workers in hospitals is a major concern during the COVID-19 pandemic.
Being exposed for several working hours per day to infected patients, nurses dealing with …

Review Article: Sarcopenia: Causes, Consequences, and Preventions

TJ Marcell - The Journals of Gerontology Series A: Biological …, 2003 - academic.oup.com
With the onset of advancing age, muscle tissue is gradually lost, resulting in diminished
mass and strength, a condition referred to as sarcopenia. The sequela of sarcopenia often …

Skeletal muscle mitochondria and aging: a review

CM Peterson, DL Johannsen… - Journal of aging …, 2012 - Wiley Online Library
Aging is characterized by a progressive loss of muscle mass and muscle strength. Declines
in skeletal muscle mitochondria are thought to play a primary role in this process …

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

F Demontis, R Piccirillo, AL Goldberg… - Disease models & …, 2013 - journals.biologists.com
A characteristic feature of aged humans and other mammals is the debilitating, progressive
loss of skeletal muscle function and mass that is known as sarcopenia. Age-related muscle …

[HTML][HTML] Sarcopenia: Current treatments and new regenerative therapeutic approaches

JH Lo, T Yiu, MT Ong, WY Lee - Journal of orthopaedic translation, 2020 - Elsevier
Sarcopenia is characterized by loss of muscle and reduction in muscle strength that
contributes to higher mortality rate and increased incidence of fall and hospitalization in the …

Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice

A Hiona, A Sanz, GC Kujoth, R Pamplona, AY Seo… - PloS one, 2010 - journals.plos.org
Background Aging results in a progressive loss of skeletal muscle, a condition known as
sarcopenia. Mitochondrial DNA (mtDNA) mutations accumulate with aging in skeletal …