1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Abstract 1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) has recently become a very popular
solvent or additive with applications across the spectrum of chemistry. Analysis shows that it …

The electrophilic halogenation of arenes is perhaps the simplest method to prepare aryl
halides, which are important structural motifs in agrochemicals, materials, and …

Photoelectrochemical cells are widely studied for solar energy conversion. However, they
have rarely been used for the synthesis of high added-value organic molecules. Here we …

The development of catalytic systems capable of oxygenating unactivated C–H bonds with
excellent site-selectivity and functional group tolerance under mild conditions remains a …

Here we report a contractive synthesis of multisubstituted cyclobutanes containing multiple
stereocenters from readily accessible pyrrolidines using iodonitrene chemistry. Mediated by …

An enantioselective catalytic vicinal diamination of styrenes is reported, which proceeds
under entirely intermolecular reaction control. It relies on a chirally modified aryliodine (I) …

The rapid development of radical chemistry has spurred several innovative strategies for
organic synthesis. The novel approaches for organic synthesis play a critical role in …

Explosive growth in the use of open shell reactivity, including neutral radicals and radical
ions, in the field of synthetic organic chemistry has been observed in the past decade …

Fluorinated alkyl groups are important motifs in bioactive compounds, positively influencing
pharmacokinetics, potency and conformation. The oxidative difluorination of alkenes …