Principles, potential, and limitations of ex vivo basophil activation by flow cytometry in allergology: a narrative review

DG Ebo, CH Bridts, CH Mertens, V Sabato - Journal of Allergy and Clinical …, 2021 - Elsevier
The major challenge of allergy diagnosis lies in the development of accessible and reliable
diagnostics allowing correct prediction of the clinical outcome following exposure to the …

Management of chronic urticaria in children: a clinical guideline

C Caffarelli, F Paravati, M El Hachem, M Duse… - Italian journal of …, 2019 - Springer
The aim of this guidance is to provide recommendations to clinicians and other interested
parties on chronic urticaria in children. The Italian Society for Pediatrics (SIP), the Italian …

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

T Zuberbier, W Aberer, R Asero, AH Abdul Latiff… - Allergy, 2018 - Wiley Online Library
This evidence‐and consensus‐based guideline was developed following the methods
recommended by Cochrane and the Grading of Recommendations Assessment …

Urticaria in children and adolescents: an updated review of the pathogenesis and management

AV Kudryavtseva, KA Neskorodova… - Pediatric Allergy and …, 2019 - Wiley Online Library
The present survey represents the latest data on diagnosis and management of childhood
urticaria. It has been observed that urticaria occurs less often in children than adults, with …

What basophil testing tells us about CSU patients–results of the CORSA study

J Marcelino, K Baumann, PS Skov… - Frontiers in …, 2021 - frontiersin.org
Basophil testing is the most effective single approach for diagnosing type-IIb autoimmune
chronic spontaneous urticaria (TIIbaiCSU). A positive basophil test has been linked to long …

Evaluating comorbidities, natural history, and predictors of early resolution in a cohort of children with chronic urticaria

E Netchiporouk, D Sasseville, L Moreau… - JAMA …, 2017 - jamanetwork.com
Importance Chronic urticaria (CU) affects 0.1% to 0.3% of children. Most cases have no
identifiable trigger and are classified as chronic spontaneous urticaria (CSU). At least half of …

Prominent role of type 2 immunity in skin diseases: beyond atopic dermatitis

L Belmesk, A Muntyanu, E Cantin… - Journal of …, 2022 - journals.sagepub.com
Type 2 immunity, illustrated by T helper 2 lymphocytes (Th2) and downstream cytokines (IL-
4, IL-13, IL-31) as well as group 2 innate lymphoid cells (ILC2), is important in host defense …

Recent advances in clinical allergy and immunology

D Simon - International archives of allergy and immunology, 2018 - karger.com
Allergic diseases are of great concern because of their high prevalence, which is still rising
in several regions, their impact on patients' physical and psychological health, the huge …

Mast cell activation tests by flow cytometry: A new diagnostic asset?

J Elst, MLM van der Poorten… - Clinical & …, 2021 - Wiley Online Library
Since the late nineties, evidence has accumulated that flow‐assisted basophil activation test
(BAT) might be an accessible and reliable method to explore the mechanisms governing …

Comorbidities of Chronic Urticaria: A glimpse into a complex relationship

N Papapostolou, P Xepapadaki, A Katoulis… - Frontiers in …, 2022 - frontiersin.org
Chronic Urticaria (CU) is a chronic inflammatory, predominantly mast cell-driven disease,
characterized by the development of wheals and/or angioedema for more than 6 weeks. It …