Advancements in understanding skin aging mechanisms, which encompass both external
and internal aging processes, have spurred the development of innovative treatments …

Graphene-based nanomaterials (GBNs) consist of a single or few layers of graphene sheets
or modified graphene including pristine graphene, graphene nanosheets (GNS), graphene …

DNA double-strand breaks (DSBs) elicit an elaborate response to signal damage and trigger
repair via two major pathways: nonhomologous end-joining (NHEJ), which functions …

Background Polyploidization, a process where cells acquire additional chromosome sets, is
a unique characteristic of hepatocytes. This process has been increasingly recognized as an …

Bacterial infections are a significant obstacle to the healing of acute and chronic wounds,
such as diabetic ulcers and burn injuries. Traditional antibiotics are the primary treatment for …

Aging is a complex biological process characterized by a gradual deterioration in
physiological activities, contributing to an elevated risk of different age-associated …

Aim Schizophrenia (SZ) is a severe psychiatric disorder caused by the interaction of genetic
and environmental factors. Although somatic mutations that occur in the brain after …

Mitochondrial genomic integrity is a key element of physiological processes and health.
Changes in the half-life of the mitochondrial genome are implicated in the generation and …

Purpose Ovarian aging is closely related to a decrease in follicular reserve and oocyte
quality. The precise molecular mechanisms underlying these reductions have yet to be fully …

Genomic interstrand crosslinks (ICLs) are formed by reactive species generated during
normal cellular metabolism, produced by the microbiome, and employed in cancer …