The heart is uniquely responsible for providing its own blood supply through the coronary
circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of …

The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

Whole body exercise tolerance is the consummate example of integrative physiological
function among the metabolic, neuromuscular, cardiovascular, and respiratory systems …

To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

The early detection of atherosclerotic disease is vital to the effective prevention and
management of life-threatening cardiovascular events such as myocardial infarctions and …

Every 34 seconds an American experiences a myocardial infarction or cardiac death.
Approximately 80% of these coronary artery disease (CAD)-related deaths are attributable to …

The human cardiovascular system is a complex arrangement of specialized structures with
distinct functions. The molecular landscape, including the genome, transcriptome and …

Exercise training (EX) induces increases in coronary transport capacity through adaptations
in the coronary microcirculation including increased arteriolar diameters and/or densities …

Background—This investigation examined the mechanisms by which coronary perivascular
adipose tissue (PVAT)–derived factors influence vasomotor tone and the PVAT proteome in …

Metabolic syndrome (MetS), a compilation of associated risk factors, increases the risk of
type 2 diabetes and coronary artery disease (CAD, atherosclerosis), which can progress to …