Abstract Nearly 60 years ago, Alan Turing showed theoretically how two chemical species,
termed morphogens, diffusing and reacting with each other can generate spatial patterns …

As cells grow, the size and number of their internal organelles increase in order to keep up
with increased metabolic requirements. Abnormal size of organelles is a hallmark of cancer …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Summary Myosin XVa (MyoXVa) and its cargo whirlin are implicated in deafness and
vestibular dysfunction and have been shown to localize at stereocilia tips and to be essential …

Two proteins implicated in inherited deafness, myosin IIIa, a plus-end-directed motor, and
espin,,,, an actin-bundling protein containing the actin-monomer-binding motif WH2, have …

Even distribution of peroxisomes (POs) and lipid droplets (LDs) is critical to their role in lipid
and reactive oxygen species homeostasis. How even distribution is achieved remains …

One ubiquitous cellular structure for performing various tasks, such as spreading and
migration over external surfaces, is the sheet-like protrusion called a lamellipodium, which …

The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however,
mechanisms of structural homeostasis remain poorly understood. Conflicting models …

The topographical interface of the extracellular environment has been appreciated as a
principal biophysical regulator for modulating cell functions, such as adhesion, migration …

Actin-bundling proteins are identified as key players in the morphogenesis of thin membrane
protrusions. Until now, functional redundancy among the actin-bundling proteins villin …