Emerging delivery approaches for targeted pulmonary fibrosis treatment

R Diwan, HN Bhatt, E Beaven, M Nurunnabi - Advanced drug delivery …, 2024 - Elsevier
Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

Docetaxel: An update on its molecular mechanisms, therapeutic trajectory and nanotechnology in the treatment of breast, lung and prostate cancer

M Imran, S Saleem, A Chaudhuri, J Ali… - Journal of Drug Delivery …, 2020 - Elsevier
Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …

Pharmacokinetic and pharmacodynamic evaluation of resveratrol loaded cationic liposomes for targeting hepatocellular carcinoma

S Jagwani, S Jalalpure, D Dhamecha… - ACS Biomaterials …, 2020 - ACS Publications
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
worldwide. The destructive nature of the disease makes it difficult for clinicians to manage …

Emerging drug delivery strategies for idiopathic pulmonary fibrosis treatment

M Ghumman, D Dhamecha, A Gonsalves… - European Journal of …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a debilitating and fatal condition that causes severe
scarring of the lungs. While the pathogenesis of IPF continues to be extensively studied and …

Development, optimization, and evaluation of PEGylated brucine-loaded PLGA nanoparticles

HS Elsewedy, BEA Dhubiab, MA Mahdy… - Drug delivery, 2020 - Taylor & Francis
The application of nanotechnology to drug delivery systems for cancer therapy has
progressively received great attention. The most heavily investigated approach is the …

Afatinib-loaded inhalable PLGA nanoparticles for localized therapy of non-small cell lung cancer (NSCLC)—development and in-vitro efficacy

RS Elbatanony, V Parvathaneni, NS Kulkarni… - Drug delivery and …, 2021 - Springer
Afatinib (AFA) is a potent aniline–quinazoline derivative, approved by the Food and Drug
Administration (FDA) in 2013, as a first-line treatment for metastatic non-small cell lung …

Production of prebiotic chitooligosaccharide and its nano/microencapsulation for the production of functional yoghurt

SA Ismail, HS El-Sayed, B Fayed - Carbohydrate polymers, 2020 - Elsevier
Production and potential application of chitooligosaccharide is reported in this study.
Chitooligosaccharide was produced by enzymatic hydrolysis of chitosan using Bacillus …

[HTML][HTML] Anticancer drug delivery: Investigating the impacts of viscosity on lipid-based formulations for pulmonary targeting

AM Thevarkattil, S Yousaf, C Houacine, W Khan… - International Journal of …, 2024 - Elsevier
Pulmonary drug delivery via aerosolization is a non-intrusive method for achieving localized
and systemic effects. The aim of this study was to establish the impact of viscosity as a novel …

Engineering porous PLGA microparticles for pulmonary delivery of sildenafil citrate

REL Lazo, B de Paula Oliveira, A de Fátima Cobre… - Powder Technology, 2023 - Elsevier
Orally administered Sildenafil (SDF) is used to treat pulmonary arterial hypertension.
However, it has a relatively low bioavailability of approximately 40%. To circumvent such …

pH-sensitive HPMCP-chitosan nanoparticles containing 5-aminosalicylic acid and berberine for oral colon delivery in a rat model of ulcerative colitis

S Mahami, M Salehi, M Mehrabi, H Vahedi… - International Journal of …, 2023 - Elsevier
Ulcerative colitis (UC) with continuous and extensive inflammation is limited to the colon
mucosa and can lead to abdominal pain, diarrhea, and rectal bleeding. Conventional …