The Pax gene family encodes a group of transcription factors that have been conserved
through millions of years of evolution and play roles in early development. Pax proteins have …

Eye development has been a paradigm for the study of organogenesis, from the
demonstration of lens induction through epithelial tissue morphogenesis, to neuronal …

We have isolated a novel otx-like homeobox gene, Crx, from the mouse retina. Crx
expression is restricted to developing and mature photoreceptor cells. CRX bound and …

The gene apparently responsible for a heritable form of murine pituitary-dependent dwarfism
(Ames dwarf, df) has been positionally cloned, identifying a novel, tissue-specific, paired-like …

The otd/Otx gene family encodes paired-like homeodomain proteins that are involved in the
regulation of anterior head structure and sensory organ development. Using the yeast one …

The symbiotic association of legumes with rhizobia involves bacterially derived Nod factor,
which is sufficient to activate the formation of nodules on the roots of the host plant …

Stat1 and Stat3 are two members of the ligand-activated transcription factor family that serve
the dual functions of signal transducers and activators of transcription. Whereas the two …

▪ Abstract Pax-6 is a member of the Pax gene class and encodes a protein containing a
paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …

Understanding brain development remains a major challenge at the heart of understanding
what makes us human. The neocortex, in evolutionary terms the newest part of the cerebral …

PAX proteins function as transcription factors and play an essential role in organogenesis
during embryonic development in regulating cell proliferation and self-renewal, resistance to …