Epidemiology of peritoneal dialysis outcomes

AK Bello, IG Okpechi, MA Osman, Y Cho… - Nature Reviews …, 2022 - nature.com
Peritoneal dialysis (PD) is an important home-based treatment for kidney failure and
accounts for 11% of all dialysis and 9% of all kidney replacement therapy globally. Although …

The impact of CKD on uremic toxins and gut microbiota

J Rysz, B Franczyk, J Ławiński, R Olszewski… - Toxins, 2021 - mdpi.com
Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

The gut microbiome, kidney disease, and targeted interventions

A Ramezani, DS Raj - Journal of the American Society of …, 2014 - journals.lww.com
The human gut harbors> 100 trillion microbial cells, which influence the nutrition,
metabolism, physiology, and immune function of the host. Here, we review the quantitative …

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut

HM Roager, L Hansen, MI Bahl, HL Frandsen… - Nature …, 2016 - nature.com
Little is known about how colonic transit time relates to human colonic metabolism and its
importance for host health, although a firm stool consistency, a proxy for a long colonic …

The effects of nutrition on the gastrointestinal microbiome of cats and dogs: impact on health and disease

SM Wernimont, J Radosevich, MI Jackson… - Frontiers in …, 2020 - frontiersin.org
The gastrointestinal (GI) microbiome of cats and dogs is increasingly recognized as a
metabolically active organ inextricably linked to pet health. Food serves as a substrate for …

p-Cresyl Sulfate

T Gryp, R Vanholder, M Vaneechoutte, G Glorieux - Toxins, 2017 - mdpi.com
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several
uremic solutes are retained. Some of these exert toxic effects, which are called uremic …

Role of the gut microbiome in uremia: a potential therapeutic target

A Ramezani, ZA Massy, B Meijers, P Evenepoel… - American Journal of …, 2016 - Elsevier
Also known as the “second human genome,” the gut microbiome plays important roles in
both the maintenance of health and the pathogenesis of disease. The symbiotic relationship …

Chronic kidney disease: role of diet for a reduction in the severity of the disease

T Naber, S Purohit - Nutrients, 2021 - mdpi.com
Chronic kidney disease affects~ 37 million adults in the US, and it is often undiagnosed due
to a lack of apparent symptoms in early stages. Chronic kidney disease (CKD) interferes with …

The gut–kidney axis

P Evenepoel, R Poesen, B Meijers - Pediatric Nephrology, 2017 - Springer
The host–gut microbiota interaction has been the focus of increasing interest in recent years.
It has been determined that this complex interaction is not only essential to many aspects of …

Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential

H Krukowski, S Valkenburg, AM Madella… - Nature Reviews …, 2023 - nature.com
Interest in gut microbiome dysbiosis and its potential association with the development and
progression of chronic kidney disease (CKD) has increased substantially in the past 6 years …