An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment

K El Karoui, AS De Vriese - Kidney International, 2022 - Elsevier
The COVID-19 pandemic has profound adverse effects on the population on dialysis.
Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality …

[HTML][HTML] Vaccination in patients with kidney failure: lessons from COVID-19

N Babel, C Hugo, TH Westhoff - Nature Reviews Nephrology, 2022 - nature.com
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …

[HTML][HTML] Seroresponse to SARS-CoV-2 vaccines among maintenance dialysis patients over 6 months

CM Hsu, DE Weiner, HJ Manley, GN Aweh… - Clinical Journal of the …, 2022 - journals.lww.com
Results Among 1870 patients receiving maintenance dialysis, 1569 had no prior COVID-19.
Patients without prior COVID-19 had declining titers over time. Among 443 recipients of …

[HTML][HTML] Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

J Bassi, O Giannini, C Silacci-Fregni, L Pertusini… - PLoS …, 2022 - journals.plos.org
Patients on dialysis are at risk of severe course of SARS-CoV-2 infection. Understanding the
neutralizing activity and coverage of SARS-CoV-2 variants of vaccine-elicited antibodies is …

[HTML][HTML] Immunogenicity of ChAdOx1 nCoV-19 vaccine after a two-dose inactivated SARS-CoV-2 vaccination of dialysis patients and kidney transplant recipients

J Bruminhent, C Setthaudom, R Kitpermkiat… - Scientific Reports, 2022 - nature.com
Vaccination with inactivated SARS-CoV-2 virus produces suboptimal immune responses
among kidney transplant (KT), peritoneal dialyzed (PD), and hemodialyzed (HD) patients …

[HTML][HTML] Antibody response to mRNA vaccines against SARS-CoV-2 with chronic kidney disease, hemodialysis, and after kidney transplantation

L Buchwinkler, CA Solagna, J Messner… - Journal of clinical …, 2021 - mdpi.com
Most trials on mRNA vaccines against SARS-CoV-2 did not include patients with chronic
kidney disease (CKD), hemodialysis (HD) patients, or kidney transplant recipients (KTR) …

[HTML][HTML] Humoral response and SARS-CoV-2 infection risk following the third and fourth doses of the BNT162b2 vaccine in dialysis patients

Y Einbinder, J Perl, N Nacasch, A Bnaya… - American Journal of …, 2022 - karger.com
The optimal SARS-CoV-2 vaccination schedule in dialysis patients and the potential need
for a fourth vaccine dose are debatable. We prospectively assessed the humoral responses …

[HTML][HTML] COVID-19 vaccination in patients receiving dialysis

B Wilde, J Korth, M Jahn, A Kribben - Nature Reviews Nephrology, 2021 - nature.com
Patients receiving dialysis are at high risk of contracting SARS-CoV-2 and developing
severe COVID-19. Established SARS-CoV-2 vaccination schemes might lack efficacy in …

[HTML][HTML] Differences in SARS-CoV-2-specific antibody responses after the first, second, and third doses of BNT162b2 in naïve and previously infected individuals: a 1 …

M Ogrič, P Žigon, E Podovšovnik, K Lakota… - Frontiers in …, 2022 - frontiersin.org
Background Safe and effective vaccines against COVID-19 are critical for preventing the
spread of SARS-CoV-2, but little is known about the humoral immune response more than 9 …