Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

Adverse childhood experiences (ACEs) are stressful or potentially traumatic events that
children experience before age 18 years. The term ACEs was coined in 1998 following the …

One proposed pathway that mindfulness-based interventions (MBIs) may offer a salutogenic
effect on somatic disorders is by enhancing immune function. As such, we conducted a meta …

Major depression is a devastating disease affecting an increasing number of people from a
young age worldwide, a situation that is expected to be worsened by the COVID-19 …

Various external stressors and environmental challenges lead to the provocation of the
immune system in autoimmune diseases like Rheumatoid arthritis (RA). The inappropriate …

Chronic stress is associated with the accelerated aging of the immune system and
represents a potent risk factor for the development and progression of a wide range of …

Ketamine is an N-methyl-d-aspartate antagonist which is increasingly being researched and
used as a treatment for depression. In low doses, it can cause a transitory modification in …

Background: Recovery of patients with rheumatoid arthritis (RA) depends on several
physical and psychological factors, besides pharmacological treatment. Co-morbid …

Mindfulness-based interventions and psychedelic-assisted therapy have been
experimentally utilised in recent years as alternative treatments for various …