Bacteria‐based cancer immunotherapy

X Huang, J Pan, F Xu, B Shao, Y Wang… - Advanced …, 2021 - Wiley Online Library
In the past decade, bacteria‐based cancer immunotherapy has attracted much attention in
the academic circle due to its unique mechanism and abundant applications in triggering the …

Drug conjugates for targeting regulatory T cells in the tumor microenvironment: guided missiles for cancer treatment

J Yang, H Bae - Experimental & Molecular Medicine, 2023 - nature.com
Within the tumor microenvironment (TME), regulatory T cells (Tregs) play a key role in
suppressing anticancer immune responses; therefore, various strategies targeting Tregs are …

Host-directed therapies: modulating inflammation to treat tuberculosis

S Krug, S Parveen, WR Bishai - Frontiers in immunology, 2021 - frontiersin.org
Following infection with Mycobacterium tuberculosis, the causative agent of tuberculosis
(TB), most human hosts are able to contain the infection and avoid progression to active TB …

Acute myeloid leukaemia and the immune system: implications for immunotherapy

AJ Barrett - British Journal of Haematology, 2020 - Wiley Online Library
The recognition of the curative potential of the graft‐versus‐leukaemia effect for patients with
acute myeloid leukaemia (AML) undergoing stem cell transplantation, and the emergence of …

Acute myeloid leukemia: from biology to clinical practices through development and pre-clinical therapeutics

X Roussel, E Daguindau, A Berceanu… - Frontiers in …, 2020 - frontiersin.org
Recent studies have provided several insights into acute myeloid leukemia. Studies based
on molecular biology have identified eight functional mutations involved in leukemogenesis …

“To be or not to Be”: Regulatory T cells in melanoma

YS Ibrahim, AH Amin, ZH Jawhar, MA Alghamdi… - International …, 2023 - Elsevier
In spite of progresses in the therapy of different malignancies, melanoma still remains as
one of lethal types of skin tumor. Melanoma is almost easily treatable by surgery alone with …

Emerging drug targets for triple-negative breast cancer: a guided tour of the preclinical landscape

X Xie, J Lee, T Iwase, M Kai… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) is the most fatal molecular subtype of
breast cancer because of its aggressiveness and resistance to chemotherapy. FDA …

[图书][B] Alpha-fetoprotein and Its Receptor in Fixing the Cancer Brakes

VN Pak - 2021 - books.google.com
This book examines the crucial role of a unique alpha-fetoprotein (AFP) in the treatment of
cancer. AFP can deliver toxins through specific receptors re-expressed in the majority of …

Role of glutamine metabolism in tuberculosis pathogenesis: a mini review

S Parveen, WR Bishai - Frontiers in Tuberculosis, 2024 - frontiersin.org
Mycobacterium tuberculosis (Mtb) has remained one of the major infectious disease killers
for generations and generations. In 2023 alone, this ancient disease was responsible for the …

EGF-IL2 bispecific and bivalent EGF fusion toxin efficacy against syngeneic head and neck cancer mouse models

Y Qiu, Z Qi, Z Wang, Y Cao, L Lu… - Oncology …, 2022 - spandidos-publications.com
The epidermal growth factor receptor (EGFR) remains one of the best molecules for
developing targeted therapy for multiple human malignancies, including head and neck …