Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Stroke is one of the leading causes of death and physical disability worldwide. The
consequences of stroke injuries are profound and persistent, causing in considerable …

Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

There is currently no approved neuroprotective pharmacotherapy for acute conditions such
as stroke and cerebral asphyxia. One of the reasons for this may be the multiplicity of cell …

Caspases are cysteine proteases that mediate apoptosis, which is a form of regulated cell
death that effectively and efficiently removes extra and unnecessary cells during …

Osteocyte apoptosis is spatially and temporally linked to bone fatigue‐induced
microdamage and to subsequent intracortical remodeling. Specifically, osteocytes …

Programmed cell death (PCD) is an ordered and tightly controlled set of changes in gene
expression and protein activity that results in neuronal cell death during brain development …

Cerebral ischemia/reperfusion (I/R) injury triggers multiple and distinct but overlapping cell
signaling pathways, which may lead to cell survival or cell damage. There is overwhelming …

The pathogenesis of many diseases is most closely connected with aberrantly regulated
apoptotic cell death. The past 15 years have witnessed an explosion in the basic knowledge …