Chemoproteomics, A Broad Avenue to Target Deconvolution

Y Gao, M Ma, W Li, X Lei - Advanced Science, 2024 - Wiley Online Library
As a vital project of forward chemical genetic research, target deconvolution aims to identify
the molecular targets of an active hit compound. Chemoproteomics, either with chemical …

QSAR, Molecular Docking, and Dynamics-Based Computational discovery of Potential PLK4 Inhibitors for tumor therapy

Y Liu, JB Tong, X Fan - Process Biochemistry, 2024 - Elsevier
Abstract PLK4 (polo-like kinase 4), an enzyme regulating centrioles, has been identified as a
highly promising target for cancer treatment, making the development of PLK4 inhibitors …

QSAR, Molecular Docking, and Dynamics-Based Computational Discovery of Potential PLK4 Inhibitors Against Tumor

Y Liu, J Tong, X Fan, Y Xing - Available at SSRN 4720290 - papers.ssrn.com
Abstract PLK4 (polo-like kinase 4), an enzyme regulating centrioles, has been identified as a
highly promising target for cancer treatment, making the development of PLK4 inhibitors …