Cross-reactive immunity among flaviviruses
APS Rathore, AL St. John - Frontiers in immunology, 2020 - frontiersin.org
Flaviviruses consist of significant human pathogens responsible for hundreds of millions of
infections each year. Their antigenic relationships generate immune responses that are …
infections each year. Their antigenic relationships generate immune responses that are …
A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2
Effective countermeasures against the recent emergence and rapid expansion of the 2019
novel coronavirus (SARS-CoV-2) require the development of data and tools to understand …
novel coronavirus (SARS-CoV-2) require the development of data and tools to understand …
Protective and enhancing interactions among dengue viruses 1-4 and Zika virus
Dengue viruses 1-4 (DENV 1-4) and Zika virus (ZIKV) are closely related flaviviruses
transmitted by Aedes mosquitoes that co-circulate in Asia, the Americas, Africa, and …
transmitted by Aedes mosquitoes that co-circulate in Asia, the Americas, Africa, and …
Older adults lack SARS CoV-2 cross-reactive T lymphocytes directed to human coronaviruses OC43 and NL63
G Saletti, T Gerlach, JM Jansen, A Molle, H Elbahesh… - Scientific reports, 2020 - nature.com
Currently, infections with SARS-Coronavirus-2 (SARS-CoV-2), the causative agent of the
COVID-19 pandemic, are responsible for substantial morbidity and mortality worldwide …
COVID-19 pandemic, are responsible for substantial morbidity and mortality worldwide …
Circulating T cell-monocyte complexes are markers of immune perturbations
JG Burel, M Pomaznoy, CS Lindestam Arlehamn… - Elife, 2019 - elifesciences.org
Our results highlight for the first time that a significant proportion of cell doublets in flow
cytometry, previously believed to be the result of technical artifacts and thus ignored in data …
cytometry, previously believed to be the result of technical artifacts and thus ignored in data …
Epitope prediction and identification-adaptive T cell responses in humans
Epitopes, in the context of T cell recognition, are short peptides typically derived by antigen
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …
T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species
Members of the flavivirus genus share a high level of sequence similarity and often circulate
in the same geographical regions. However, whether T cells induced by one viral species …
in the same geographical regions. However, whether T cells induced by one viral species …
Long-term persistence of infectious Zika virus: inflammation and behavioral sequela in mice
DDC Ireland, M Manangeeswaran… - Plos …, 2020 - journals.plos.org
The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well
documented, however the potential defects and long-term consequences associated with …
documented, however the potential defects and long-term consequences associated with …
[HTML][HTML] Current understanding of the role of T cells in chikungunya, dengue and zika infections
Arboviral infections such as Chikungunya (CHIKV), Dengue (DENV) and Zika (ZIKV) are a
major disease burden in tropical and sub-tropical countries, and there are no effective …
major disease burden in tropical and sub-tropical countries, and there are no effective …
Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures
Parkinson's disease (PD) is a multi-stage neurodegenerative disorder with largely unknown
etiology. Recent findings have identified PD-associated autoimmune features including …
etiology. Recent findings have identified PD-associated autoimmune features including …