The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential
GW Zamponi, J Striessnig, A Koschak… - Pharmacological …, 2015 - Elsevier
Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …
review, the different subtypes of voltage-gated calcium channels are described and their …
Neuronal voltage-gated calcium channels: structure, function, and dysfunction
BA Simms, GW Zamponi - Neuron, 2014 - cell.com
Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
Calcium-permeable ion channels in pain signaling
The detection and processing of painful stimuli in afferent sensory neurons is critically
dependent on a wide range of different types of voltage-and ligand-gated ion channels …
dependent on a wide range of different types of voltage-and ligand-gated ion channels …
Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's disease
J Duda, C Pötschke, B Liss - Journal of neurochemistry, 2016 - Wiley Online Library
Dopamine‐releasing neurons within the Substantia nigra (SN DA) are particularly
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …
vulnerable to degeneration compared to other dopaminergic neurons. The age‐dependent …
Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances
ZM Khaliq, BP Bean - Journal of Neuroscience, 2010 - Soc Neuroscience
Dopaminergic neurons in the ventral tegmental area (VTA) fire spontaneously in a
pacemaker-like manner. We analyzed the ionic currents that drive pacemaking in …
pacemaker-like manner. We analyzed the ionic currents that drive pacemaking in …
Activation of the Cl− Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP3 Receptor
X Jin, S Shah, Y Liu, H Zhang, M Lees, Z Fu… - Science …, 2013 - science.org
We report that anoctamin 1 (ANO1; also known as TMEM16A) Ca2+-activated Cl− channels
in small neurons from dorsal root ganglia are preferentially activated by particular pools of …
in small neurons from dorsal root ganglia are preferentially activated by particular pools of …
T-type calcium channels: from molecule to therapeutic opportunities
N Weiss, GW Zamponi - The international journal of biochemistry & cell …, 2019 - Elsevier
T-type calcium channels serve an essential role in the functioning of the nervous system.
They exhibit unique properties among voltage-gated calcium channels, and mediate specific …
They exhibit unique properties among voltage-gated calcium channels, and mediate specific …
[HTML][HTML] Dopamine midbrain neurons in health and Parkinson's disease: emerging roles of voltage-gated calcium channels and ATP-sensitive potassium channels
E Dragicevic, J Schiemann, B Liss - Neuroscience, 2015 - Elsevier
Dopamine (DA) releasing midbrain neurons are essential for multiple brain functions, such
as voluntary movement, working memory, emotion and cognition. DA midbrain neurons …
as voluntary movement, working memory, emotion and cognition. DA midbrain neurons …
Sexually dimorphic neuronal responses to social isolation
L Senst, D Baimoukhametova, TL Sterley, JS Bains - elife, 2016 - elifesciences.org
Many species use social networks to buffer the effects of stress. The mere absence of a
social network, however, may also be stressful. We examined neuroendocrine, PVN CRH …
social network, however, may also be stressful. We examined neuroendocrine, PVN CRH …