Experimental evidence accumulated over decades has implicated epithelial–mesenchymal
plasticity (EMP), which collectively encompasses epithelial–mesenchymal transition and the …

Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are
genetic determinants of cellular plasticity. These programs operate in physiological …

We present the molecular landscape of pediatric acute myeloid leukemia (AML) and
characterize nearly 1,000 participants in Children's Oncology Group (COG) AML trials. The …

Reactivation of an embryonic epithelial-to-mesenchymal (EMT) program is commonly
accepted as a core component of carcinoma progression. Collectively, EMT and …

Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

CD11c+ atypical B cells (ABCs) are an alternative memory B cell lineage associated with
immunization, infection, and autoimmunity. However, the factors that drive the transcriptional …

Simple Summary Spine metastases are a common life-threatening complication of
advanced-stage malignancies and often result in poor prognosis. Symptomatic spine …

Acute leukemias (ALs) of ambiguous lineage are a heterogeneous group of high-risk
leukemias characterized by coexpression of myeloid and lymphoid markers. In this study, we …

ZEB1 and ZEB2 are zinc-finger E homeobox-binding transcription factors best known for
their role in driving epithelial to mesenchymal transition. However, in recent years our …

In cancer cells, enhancer hijacking mediated by chromosomal alterations and/or increased
deposition of acetylated histone H3 lysine 27 (H3K27ac) can support oncogene expression …