Diabetic nephropathy (DN) is the most serious microvascular complication of diabetes and
the largest single cause of end‐stage renal disease (ESRD) in many developed countries …

Most medical investigations have found a reduced blood level of miR‐146a in type 2
diabetes (T2D) patients, suggesting an important role for miR‐146a (microRNA‐146a) in the …

Aims To analyze retinal vascular plexuses and choriocapillaris by optical coherence
tomography angiography (OCT-A) and retinal nerve fiber layer and ganglion cell layer (GCL) …

Hyperglycemia induced endothelial injury is a key pathogenetic factor in diabetic
cardiomyopathy. In diabetes, changes in pro-inflammatory cytokines are a key mechanism …

MicroRNA-146a (miR-146a) regulates multiple immune diseases. However, the role of miR-
146a in diabetic peripheral neuropathy (DPN) has not been investigated. We found that …

Chronic kidney disease is a worldwide health crisis, while diabetic kidney disease (DKD)
has become the leading cause of end-stage renal disease (ESRD). DKD is a microvascular …

Purpose Intravitreal anti-vascular endothelial growth factor agents have been shown to
reduce diabetic retinopathy (DR) progression; data on the effects of intravitreal …

Aims Recent studies have identified neuroretinal abnormalities in persons affected by
diabetes mellitus, before the onset of microvascular alterations. However, the role of …

In the last decade, miRNAs have received substantial attention as potential players of
diabetes microvascular complications, affecting the kidney, the retina, and the peripheral …

Diabetic retinopathy (DR) accounts for~ 80% of legal blindness in persons aged 20–74
years and is associated with enormous social and health burdens. Current therapies are …