The biology and functional importance of MAIT cells
DI Godfrey, HF Koay, J McCluskey, NA Gherardin - Nature immunology, 2019 - nature.com
In recent years, a population of unconventional T cells called 'mucosal-associated invariant
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their …
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their …
MAIT cells in health and disease
NM Provine, P Klenerman - Annual review of immunology, 2020 - annualreviews.org
Mucosal-associated invariant T (MAIT) cells have been attracting increasing attention over
the last few years as a potent unconventional T cell subset. Three factors largely account for …
the last few years as a potent unconventional T cell subset. Three factors largely account for …
TCR-or cytokine-activated CD8+ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses
R Lamichhane, M Schneider, SM de la Harpe… - Cell reports, 2019 - cell.com
Mucosal-associated invariant T (MAIT) cells can be activated via either their T cell receptor
(TCR), which recognizes MR1-bound pyrimidines derived from microbial riboflavin …
(TCR), which recognizes MR1-bound pyrimidines derived from microbial riboflavin …
[HTML][HTML] MAIT cells, guardians of skin and mucosa?
I Nel, L Bertrand, A Toubal, A Lehuen - Mucosal immunology, 2021 - Elsevier
Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …
Mucosal-associated invariant T cells for cancer immunotherapy
Human mucosal-associated invariant T (MAIT) cells are characterized by their expression of
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses
A Chancellor, R Alan Simmons, RC Khanolkar… - Journal of Experimental …, 2023 - rupress.org
Mucosal-associated invariant T (MAIT) cells use canonical semi-invariant T cell receptors
(TCR) to recognize microbial riboflavin precursors displayed by the antigen-presenting …
(TCR) to recognize microbial riboflavin precursors displayed by the antigen-presenting …
MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity
Protective immune responses against respiratory pathogens, such as severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus, are initiated by the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus, are initiated by the …
Interleukin (IL)-12 and IL-18 synergize to promote MAIT cell IL-17A and IL-17F production independently of IL-23 signaling
S Cole, J Murray, C Simpson, R Okoye… - Frontiers in …, 2020 - frontiersin.org
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for
inducing IL-17 production in other human immune subsets remains incompletely …
inducing IL-17 production in other human immune subsets remains incompletely …
Insights into mucosal-associated invariant T cell biology from studies of invariant natural killer T cells
Mucosal-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells are
innate-like T cells that function at the interface between innate and adaptive immunity. They …
innate-like T cells that function at the interface between innate and adaptive immunity. They …
Dendritic cells and programmed death-1 blockade: a joint venture to combat cancer
M Versteven, JMJ Van den Bergh, E Marcq… - Frontiers in …, 2018 - frontiersin.org
Two decades of clinical cancer research with dendritic cell (DC)-based vaccination have
proved that this type of personalized medicine is safe and has the capacity to improve …
proved that this type of personalized medicine is safe and has the capacity to improve …