Systemic mitochondrial dysfunction, dopamine loss, sustained structural changes in the
basal ganglia including reduced tyrosine hydroxylase, and altered gait-these effects …

The application of omics to study Caenorhabditis elegans (C. elegans) in the context of
spaceflight is increasing, illuminating the wide-ranging biological impacts of spaceflight on …

Sarcopenia is a geriatric syndrome characterized by an age‐related decline in skeletal
muscle mass and strength. Here, we show that suppression of mitochondrial calcium …

While spaceflight is becoming more common than before, the hazards spaceflight and space
microgravity pose to the human body remain relatively unexplored. Astronauts experience …

Mitochonic Acid 5 (MA-5) enhances mitochondrial ATP production, restores fibroblasts from
mitochondrial disease patients and extends the lifespan of the disease model “Mitomouse” …

Background: Understanding and countering the well-established negative health
consequences of spaceflight remains a primary challenge preventing safe deep space …

Fighting stress-related effects during spaceflight is crucial for a successful mission.
Emotional, motivational, and cognitive mechanisms have already been shown to be …

We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …

From both environment and health perspectives, sustainable management of ever-growing
soil contamination by heavy metal is posing a serious global concern. The potential …

The space environment presents unique stressors, such as microgravity and space
radiation, which can induce molecular and physiological changes in living organisms. To …