Network-based methods for predicting essential genes or proteins: a survey
Genes that are thought to be critical for the survival of organisms or cells are called essential
genes. The prediction of essential genes and their products (essential proteins) is of great …
genes. The prediction of essential genes and their products (essential proteins) is of great …
Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19
Abstract Objectives Coronavirus disease 2019 (COVID‐19) is rapidly spreading worldwide.
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19 …
[HTML][HTML] Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular …
Y Wang, Y Yuan, W Wang, Y He, H Zhong… - Computers in biology …, 2022 - Elsevier
Background Qingfeiyin (QFY) is a common Chinese herbal formula for the treatment of acute
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …
A review of bioinformatics tools and web servers in different microarray platforms used in cancer research
Over the past decade, conventional lab work strategies have gradually shifted from being
limited to a laboratory setting towards a bioinformatics era to help manage and process the …
limited to a laboratory setting towards a bioinformatics era to help manage and process the …
lncRNA/circRNA‑miRNA‑mRNA ceRNA network in lumbar intervertebral disc degeneration
J Zhu, X Zhang, W Gao, H Hu… - Molecular medicine …, 2019 - spandidos-publications.com
Accumulating evidence has indicated that noncoding RNAs are involved in intervertebral
disc degeneration (IDD); however, the competing endogenous RNA (ceRNA)‑mediated …
disc degeneration (IDD); however, the competing endogenous RNA (ceRNA)‑mediated …
Network learning for biomarker discovery
Everything is connected and thus networks are instrumental in not only modeling complex
systems with many components, but also accommodating knowledge about their …
systems with many components, but also accommodating knowledge about their …
Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
Inflammasomes are involved in gut homeostasis and inflammatory pathologies, but the role
of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated …
of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated …
A systematic survey of centrality measures for protein-protein interaction networks
M Ashtiani, A Salehzadeh-Yazdi… - BMC systems …, 2018 - Springer
Background Numerous centrality measures have been introduced to identify “central” nodes
in large networks. The availability of a wide range of measures for ranking influential nodes …
in large networks. The availability of a wide range of measures for ranking influential nodes …
Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms
Y Wan, L Xu, Z Liu, M Yang, X Jiang, Q Zhang… - … and alternative medicine, 2019 - Springer
Abstract Background Wumei Pill (WMP), a famous herbal formula, has been widely used to
treat digestive system diseases in clinical practice in China for centuries. We have found a …
treat digestive system diseases in clinical practice in China for centuries. We have found a …
A quantitative inventory of yeast P body proteins reveals principles of composition and specificity
P bodies are archetypal biomolecular condensates that concentrate proteins and RNA
without a surrounding membrane. While dozens of P body proteins are known, the …
without a surrounding membrane. While dozens of P body proteins are known, the …