[HTML][HTML] COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/mL 25 (OH) D3 …

L Borsche, B Glauner, J von Mendel - Nutrients, 2021 - mdpi.com
Background: Open Access Editor's Choice Systematic Review COVID-19 Mortality Risk
Correlates Inversely with Vitamin D3 Status, and a Mortality Rate Close to Zero Could …

[HTML][HTML] Melatonin as a potential approach to anxiety treatment

K Repova, T Baka, K Krajcirovicova, P Stanko… - International journal of …, 2022 - mdpi.com
Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

[HTML][HTML] Endocrine and metabolic complications of COVID-19: lessons learned and future prospects

A Esmaeilzadeh, R Elahi… - Journal of …, 2022 - jme.bioscientifica.com
Coronavirus disease 2019 (COVID-19) is well known for its respiratory complications;
however, it can also cause extrapulmonary manifestations, including cardiovascular …

[HTML][HTML] The impact of microRNAs in renin–angiotensin-system-induced cardiac remodelling

M Adamcova, I Kawano, F Simko - International Journal of Molecular …, 2021 - mdpi.com
Current knowledge on the renin–angiotensin system (RAS) indicates its central role in the
pathogenesis of cardiovascular remodelling via both hemodynamic alterations and direct …

[HTML][HTML] Role of the renin-angiotensin system in long COVID's cardiovascular injuries

E Cojocaru, C Cojocaru, CE Vlad, L Eva - Biomedicines, 2023 - mdpi.com
The renin-angiotensin system (RAS) is one of the biggest challenges of cardiovascular
medicine. The significance of the RAS in the chronic progression of SARS-CoV-2 infection …

[HTML][HTML] The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

S Cacanyiova, M Cebova, F Simko, T Baka… - Biological Research, 2023 - Springer
Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection
cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the …

[HTML][HTML] Effect of sacubitril/valsartan on the hypertensive heart in continuous light-induced and lactacystin-induced pre-hypertension: Interactions with the renin …

F Simko, P Stanko, K Repova, T Baka… - Biomedicine & …, 2024 - Elsevier
This study investigated whether sacubitril/valsartan or valsartan are able to prevent left
ventricular (LV) fibrotic remodelling and dysfunction in two experimental models of pre …

[HTML][HTML] Safety and efficacy of dietary epigallocatechin gallate supplementation in attenuating hypertension via its modulatory activities on the intrarenal renin …

KW Parn, WC Ling, JH Chin, SK Lee - Nutrients, 2022 - mdpi.com
This study aimed to identify the no-observed-adverse-effect level (NOAEL) of dietary
epigallocatechin gallate (EGCG) supplementation and its possible antihypertensive and …

[HTML][HTML] Sacubitril/Valsartan and Ivabradine Attenuate Left ventricular remodelling and dysfunction in spontaneously hypertensive rats: different interactions with the …

F Simko, T Baka, P Stanko, K Repova, K Krajcirovicova… - Biomedicines, 2022 - mdpi.com
This study investigated whether sacubitril/valsartan and ivabradine are able to prevent left
ventricular (LV) fibrotic remodelling and dysfunction in a rat experimental model of …

[HTML][HTML] Alternative RAS in various hypoxic conditions: from myocardial infarction to COVID-19

T Rajtik, P Galis, L Bartosova, L Paulis… - International Journal of …, 2021 - mdpi.com
Alternative branches of the classical renin–angiotensin–aldosterone system (RAS)
represent an important cascade in which angiotensin 2 (AngII) undergoes cleavage via the …