Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015
Y Zhang, WW Yew - … Journal of Tuberculosis and Lung Disease, 2015 - ingentaconnect.com
Drug-resistant tuberculosis (DR-TB), including multi-and extensively drug-resistant TB, is
posing a significant challenge to effective treatment and TB control worldwide. New progress …
posing a significant challenge to effective treatment and TB control worldwide. New progress …
[HTML][HTML] The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee
MJ Ellington, O Ekelund, FM Aarestrup… - Clinical microbiology …, 2017 - Elsevier
Whole genome sequencing (WGS) offers the potential to predict antimicrobial susceptibility
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
from a single assay. The European Committee on Antimicrobial Susceptibility Testing …
Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing
CRyPTIC Consortium and the 100,000 … - … England Journal of …, 2018 - Mass Medical Soc
Abstract Background The World Health Organization recommends drug-susceptibility testing
of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment …
of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment …
Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study
Background Diagnosing drug-resistance remains an obstacle to the elimination of
tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial …
tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial …
[HTML][HTML] Developing new antimicrobial therapies: are synergistic combinations of plant extracts/compounds with conventional antibiotics the solution?
MJ Cheesman, A Ilanko, B Blonk… - Pharmacognosy reviews, 2017 - ncbi.nlm.nih.gov
The discovery of penicillin nearly 90 years ago revolutionized the treatment of bacterial
disease. Since that time, numerous other antibiotics have been discovered from bacteria …
disease. Since that time, numerous other antibiotics have been discovered from bacteria …
Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project
Background Pyrazinamide and fluoroquinolones are essential antituberculosis drugs in new
rifampicin-sparing regimens. However, little information about the extent of resistance to …
rifampicin-sparing regimens. However, little information about the extent of resistance to …
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain
The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB)
pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy …
pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy …
The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology
Background Tracking recent transmission is a vital part of controlling widespread pathogens
such as Mycobacterium tuberculosis. Multiple methods with specific performance …
such as Mycobacterium tuberculosis. Multiple methods with specific performance …
Drug resistance mechanisms and drug susceptibility testing for tuberculosis
Tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) is the deadliest infectious
disease and the associated global threat has worsened with the emergence of drug …
disease and the associated global threat has worsened with the emergence of drug …
What is resistance? Impact of phenotypic versus molecular drug resistance testing on therapy for multi-and extensively drug-resistant tuberculosis
J Heyckendorf, S Andres, CU Köser… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi-
and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of …
and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of …