[HTML][HTML] Gut microbiota-dependent marker TMAO in promoting cardiovascular disease: inflammation mechanism, clinical prognostic, and potential as a therapeutic …

S Yang, X Li, F Yang, R Zhao, X Pan, J Liang… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …

Lipoprotein receptor signalling in atherosclerosis

C Mineo - Cardiovascular research, 2020 - academic.oup.com
The founding member of the lipoprotein receptor family, low-density lipoprotein receptor
(LDLR) plays a major role in the atherogenesis through the receptor-mediated endocytosis …

[HTML][HTML] Procoagulant Phosphatidylserine-Exposing Platelets in vitro and in vivo

EC Reddy, ML Rand - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
The physiological heterogeneity of platelets leads to diverse responses and the formation of
discrete subpopulations upon platelet stimulation. Procoagulant platelets are an example of …

The role of CD36 in cardiovascular disease

H Shu, Y Peng, W Hang, J Nie, N Zhou… - Cardiovascular …, 2022 - academic.oup.com
CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …

[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers

R Mallick, S Basak, AK Duttaroy - Progress in lipid research, 2021 - Elsevier
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

CD36 in atherosclerosis: pathophysiological mechanisms and therapeutic implications

K Tian, Y Xu, A Sahebkar, S Xu - Current atherosclerosis reports, 2020 - Springer
Abstract Purpose of Review Atherosclerosis is a chronic disease characterized by lipid
retention and inflammation in the artery wall. The retention and oxidation of low-density …

[HTML][HTML] Problems of pathogenesis and pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological …

E Gusev, A Sarapultsev, D Hu… - International journal of …, 2021 - mdpi.com
The COVID-19 pandemic examines not only the state of actual health care but also the state
of fundamental medicine in various countries. Pro-inflammatory processes extend far …

Platelet proteomes, pathways, and phenotypes as informants of vascular wellness and disease

JE Aslan - Arteriosclerosis, thrombosis, and vascular biology, 2021 - Am Heart Assoc
Platelets rapidly undergo responsive transitions in form and function to repair vascular
endothelium and mediate hemostasis. In contrast, heterogeneous platelet subpopulations …

[HTML][HTML] Is arsenic exposure a risk factor for metabolic syndrome? a review of the potential mechanisms

P Pánico, M Velasco, AM Salazar, A Picones… - Frontiers in …, 2022 - frontiersin.org
Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is
associated with increased risk of developing chronic diseases, including metabolic …

Procoagulant platelets: novel players in thromboinflammation

F Denorme, RA Campbell - American Journal of Physiology …, 2022 - journals.physiology.org
Platelets play a key role in maintaining hemostasis. However, dysregulated platelet
activation can lead to pathological thrombosis or bleeding. Once a platelet gets activated, it …