Impact of HIV-associated cognitive impairment on functional independence, frailty and quality of life in the modern era: a meta-analysis

M Nweke, N Mshunqane, N Govender, AO Akinpelu… - Scientific reports, 2022 - nature.com
HIV-associated neurocognitive disorder (HAND) is an important sequela of HIV infection.
Combined antiretroviral therapy (cART) has improved the health outcomes of many people …

Frailty: a new vulnerability indicator in people aging with HIV

TD Brothers, K Rockwood - European geriatric medicine, 2019 - Springer
Purpose To review the concept of frailty and its measurement, describe the existing data on
frailty in people living with HIV, examine the limits of frailty as a marker of vulnerability in …

Effects of comorbidity burden and age on brain integrity in HIV

R Saloner, RK Heaton, LM Campbell, A Chen… - Aids, 2019 - journals.lww.com
Objective: The influence of confounding neurocognitive comorbidities in people living with
HIV (PLWH) on neuroimaging has not been systematically evaluated. We determined …

The Combined Effects of Cannabis, Methamphetamine, and HIV on Neurocognition

JM Rogers, JE Iudicello, MCG Marcondes, EE Morgan… - Viruses, 2023 - mdpi.com
Objective: Methamphetamine and cannabis are two widely used substances among people
living with HIV (PLWH). Whereas methamphetamine use has been found to worsen HIV …

Chronically elevated depressive symptoms interact with acute increases in inflammation to predict worse neurocognition among people with HIV

R Saloner, EW Paolillo, RK Heaton, DJ Grelotti… - Journal of …, 2021 - Springer
We examined the joint effects of depressive symptoms (Beck Depression Inventory-II (BDI-
II)) and systemic inflammation (plasma C-reactive protein (CRP)) on longitudinal profiles of …

Frailty and neurocognitive impairment: impacts on quality of life in HIV

AA Rubtsova, S Sabbag, E Sundermann… - Journal of the …, 2020 - journals.lww.com
Little is known about the effects of aging-related conditions on health-related quality of life
(HRQOL) among people living with HIV (PLWH). The purpose of our study was to examine …

Mediating effects of resilience on frailty and depression among older Chinese people living with HIV/AIDS: a cross-sectional study in Hunan

M Yao, D Chen, L Meng, C Zhou… - Transactions of The Royal …, 2023 - academic.oup.com
Background Little is known about the ambiguous and complex relationship between frailty,
resilience and depression in older adults living with HIV (OALHIV). Thus, the current study …

Cognitive trajectory phenotypes in human immunodeficiency virus–infected patients

RM Dastgheyb, N Sacktor, D Franklin… - JAIDS Journal of …, 2019 - journals.lww.com
Objective: The presentation of cognitive impairments in HIV-infected individuals has
transformed since the introduction of antiretroviral therapies. Although the overall …

The association between benzodiazepine use and greater risk of neurocognitive impairment is moderated by medical burden in people with HIV

EE Sundermann, R Saloner, A Rubtsova… - Journal of …, 2022 - Springer
Benzodiazepine use is linked to neurocognitive impairment (NCI) in the general population
and people with HIV (PWH); however, this relationship may depend on age-related factors …

The structural and functional correlates of frailty in persons with human immunodeficiency virus

JF Strain, S Cooley, C Kilgore, B Nelson… - Clinical Infectious …, 2022 - academic.oup.com
Abstract Background Persons with HIV (PWH) are at increased risk of frailty, a clinically
recognizable state of increased vulnerability resulting from aging-associated decline in …