Exploration of potent antiviral phytomedicines from Lauraceae family plants against SARS-CoV-2 RNA-dependent RNA polymerase

AA Rabaan, MA Halwani, M Aljeldah… - Journal of …, 2023 - Taylor & Francis
RNA-dependent RNA polymerase, also known as RdRp, is a possible therapeutic target that
could be used to suppress the proliferation of RNA viruses such as SARS-CoV-2. This …

Identification of Antiviral Compounds against Monkeypox Virus Profilin-like Protein A42R from Plantago lanceolata

LH Bajrai, AS Alharbi, MM El-Day, AG Bafaraj… - Molecules, 2022 - mdpi.com
Infections caused by the monkeypox virus (MPXV) have continued to be transmitted
significantly in recent years. However, understanding the transmission mechanism, risk …

Computational model for disease research

X Chen, L Huang - Briefings in Bioinformatics, 2023 - academic.oup.com
Computational analysis of vast public and private omics data [1–5] generated by high-
throughput technologies [6, 7] aids in deciphering complex mechanisms [8–11] and relevant …

Diversity and pathobiology of an ilarvirus unexpectedly detected in diverse plants and global sequencing data

MPS Rivarez, C Faure, L Svanella-Dumas… - …, 2023 - Am Phytopath Society
High-throughput sequencing (HTS) and sequence mining tools revolutionized virus
detection and discovery in recent years, and implementing them with classical plant virology …

Anti-Dengue: A Machine Learning-Assisted Prediction of Small Molecule Antivirals against Dengue Virus and Implications in Drug Repurposing

S Gautam, A Thakur, A Rajput, M Kumar - Viruses, 2023 - mdpi.com
Dengue outbreaks persist in global tropical regions, lacking approved antivirals,
necessitating critical therapeutic development against the virus. In this context, we …

In Silico Protein Structure Analysis for SARS-CoV-2 Vaccines Using Deep Learning

Y Matsuzaka, R Yashiro - BioMedInformatics, 2023 - mdpi.com
Protein three-dimensional structural analysis using artificial intelligence is attracting
attention in various fields, such as the estimation of vaccine structure and stability. In …

VirusHound-I: prediction of viral proteins involved in the evasion of host adaptive immune response using the random forest algorithm and generative adversarial …

JF Beltrán, LH Belén, JG Farias… - Briefings in …, 2024 - academic.oup.com
Throughout evolution, pathogenic viruses have developed different strategies to evade the
response of the adaptive immune system. To carry out successful replication, some …

Investigation of ritonavir analogs antiretroviral natural compounds against SARS-CoV-2 envelope protein

S Negi, NK Kamboj, GB K, U Yadava - Journal of Biomolecular …, 2025 - Taylor & Francis
Since the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) was first reported from Wuhan, China, there has been a surge in scientific research …

Antiviral actions of natural compounds against dengue virus RNA dependent RNA polymerase: insights from molecular dynamics and Gibbs free energy landscape

AA Rabaan, NA Al Kaabi, Muzaheed… - Journal of …, 2024 - Taylor & Francis
Dengue fever, a major global health challenge, affects nearly half the world's population and
lacks effective treatments or vaccines. Addressing this, our study focused on natural …

Polarization analysis of gene sequence structures: Mapping of extreme local polarization states

DA Zimnyakov, MV Alonova, AV Skripal… - Journal of Biomedical …, 2022 - jbpe.ssau.ru
A method for visualization and identification of nucleotide sequences is proposed based on
the synthesis of phase screens displaying the structure of the analyzed sequences and …