Estrogen: a master regulator of bioenergetic systems in the brain and body

JR Rettberg, J Yao, RD Brinton - Frontiers in neuroendocrinology, 2014 - Elsevier
Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review

MD Klok, S Jakobsdottir, ML Drent - Obesity reviews, 2007 - Wiley Online Library
Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels

L Bonfili, V Cecarini, S Berardi, S Scarpona… - Scientific reports, 2017 - nature.com
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …

[HTML][HTML] Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition

D Rémond, DR Shahar, D Gille, P Pinto, J Kachal… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic
understanding of the impact of aging on the intake, digestion, and absorption of nutrients is …

Mechanisms of the anorexia of aging—a review

A Wysokiński, T Sobów, I Kłoszewska, T Kostka - Age, 2015 - Springer
Many, even healthy, older people fail to adequately regulate food intake and experience
loss of weight. Aging-associated changes in the regulation of appetite and the lack of hunger …

Ghrelin controls hippocampal spine synapse density and memory performance

S Diano, SA Farr, SC Benoit, EC McNay, I da Silva… - Nature …, 2006 - nature.com
The gut hormone and neuropeptide ghrelin affects energy balance and growth hormone
release through hypothalamic action that involves synaptic plasticity in the melanocortin …

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor

Y Sun, P Wang, H Zheng… - Proceedings of the …, 2004 - National Acad Sciences
Synthetic agonists of the growth hormone secretagogue receptor (GHSR) rejuvenate the
pulsatile pattern of GH-release in the elderly, and increase lean but not fat mass in obese …

Ghrelin—a hormone with multiple functions

M Korbonits, AP Goldstone, M Gueorguiev… - Frontiers in …, 2004 - Elsevier
Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Ghrelin and the short-and long-term regulation of appetite and body weight

DE Cummings - Physiology & behavior, 2006 - Elsevier
Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone.
Considerable evidence implicates ghrelin in mealtime hunger and meal initiation …

Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes

SM Poykko, E Kellokoski, S Horkko, H Kauma… - Diabetes, 2003 - Am Diabetes Assoc
Experimental studies have suggested that ghrelin plays a role in glucose homeostasis and
in the regulation of blood pressure (BP). We therefore assessed the hypothesis that a low …