Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Early life stress (ELS) developmental effects have been widely studied by preclinical
researchers. Despite the growing body of evidence from ELS models, such as the maternal …

There is growing evidence of 'food addiction'(FA) in sugar-and fat-bingeing animals. The
purpose of this study was to investigate the legitimacy of this disorder in the human …

Why Love Matters explains why loving relationships are essential to brain development in
the early years, and how these early interactions can have lasting consequences for future …

An adverse maternal hormonal environment during pregnancy can be associated with
abnormal brain growth. Subtle changes in fetal brain development have been observed …

Psychoactive substance use is a nearly universal human behavior, but a significant minority
of people who use addictive substances will go on to develop an addictive disorder …

Rationale Research on adolescence and drug abuse increased substantially in the past
decade. However, drug-addiction-related behaviors following stressful experiences during …

Stressful stimuli in healthy subjects trigger activation of a consistent and reproducible set of
brain regions; yet, the notion that there is a single and constant stress neuromatrix is not …

Early life stress, in the form of MD (24 h at pnd 9), interferes with brain developmental
trajectories modifying both behavioral and neurobiochemical parameters. MD has been …

Addiction is a chronic relapsing disorder with devastating personal, societal, and economic
consequences. In humans, early‐life adversity (ELA) such as trauma, neglect, and resource …