[HTML][HTML] Invited review: Inflammation during the transition to lactation: New adventures with an old flame

BJ Bradford, K Yuan, JK Farney, LK Mamedova… - Journal of dairy …, 2015 - Elsevier
For dairy cattle, the first several weeks of lactation represent the highest-risk period in their
lives after their own neonatal period. Although more than 50% of cows during this period are …

Leukotriene receptors as potential therapeutic targets

T Yokomizo, M Nakamura… - The Journal of clinical …, 2018 - Am Soc Clin Investig
Leukotrienes, a class of arachidonic acid–derived bioactive molecules, are known as
mediators of allergic and inflammatory reactions and considered to be important drug …

The role of leukotrienes as potential therapeutic targets in allergic disorders

A Jo-Watanabe, T Okuno, T Yokomizo - International journal of molecular …, 2019 - mdpi.com
Leukotrienes (LTs) are lipid mediators that play pivotal roles in acute and chronic
inflammation and allergic diseases. They exert their biological effects by binding to specific …

The role of leukotrienes in allergic diseases

M Liu, T Yokomizo - Allergology International, 2015 - jstage.jst.go.jp
abstract Leukotrienes (LTs), both LTB4 and the cysteinyl LTs (CysLTs) LTC4, LTD4 and
LTE4, are implicated in a wide variety of inflammatory disorders. These lipid mediators are …

In vitro wound healing assays–state of the art

A Stamm, K Reimers, S Strauß, P Vogt, T Scheper… - …, 2016 - degruyter.com
Wound healing is essential for the restoration of the barrier function of the skin. During this
process, cells at the wound edges proliferate and migrate, leading to re-epithelialization of …

Synthesis and significance of arachidonic acid, a substrate for cyclooxygenases, lipoxygenases, and cytochrome P450 pathways in the tumorigenesis of glioblastoma …

J Korbecki, E Rębacz-Maron, P Kupnicka, D Chlubek… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme is a brain tumor with a very unfavorable
prognosis, where the vast majority of patients do not survive a year after diagnosis. One line …

The role of the LTB4-BLT1 axis in health and disease

R He, Y Chen, Q Cai - Pharmacological research, 2020 - Elsevier
Abstract Leukotriene B4 (LTB4) is a major type of lipid mediator that is rapidly generated
from arachidonic acid through sequential action of 5-lipoxygenase (5-LO), 5-lipoxygenase …

[HTML][HTML] Identification, signaling, and functions of LTB4 receptors

K Saeki, T Yokomizo - Seminars in immunology, 2017 - Elsevier
Abstract Leukotriene B 4 (LTB 4), a lipid mediator produced from arachidonic acid, is a
chemoattractant for inflammatory leukocytes. We identified two receptors for LTB 4, the high …

Two distinct leukotriene B4 receptors, BLT1 and BLT2

T Yokomizo - The journal of biochemistry, 2015 - academic.oup.com
Abstract Leukotriene B4 (LTB4) is a potent inflammatory mediator derived from arachidonic
acid. Two G protein-coupled receptors for LTB4 have been identified: a high-affinity receptor …

Topical Administration of a Marine Oil Rich in Pro-Resolving Lipid Mediators Accelerates Wound Healing in Diabetic db/db Mice through Angiogenesis and …

I Ontoria-Oviedo, E Amaro-Prellezo… - International Journal of …, 2022 - mdpi.com
Impaired wound healing in patients with type 2 diabetes (DM2) is characterized by chronic
inflammation, which delays wound closure. Specialized pro-resolving lipid mediators …