T Yokomizo, M Nakamura… - The Journal of clinical …, 2018 - Am Soc Clin Investig
Leukotrienes, a class of arachidonic acid–derived bioactive molecules, are known as mediators of allergic and inflammatory reactions and considered to be important drug …
A Jo-Watanabe, T Okuno, T Yokomizo - International journal of molecular …, 2019 - mdpi.com
Leukotrienes (LTs) are lipid mediators that play pivotal roles in acute and chronic inflammation and allergic diseases. They exert their biological effects by binding to specific …
M Liu, T Yokomizo - Allergology International, 2015 - jstage.jst.go.jp
abstract Leukotrienes (LTs), both LTB4 and the cysteinyl LTs (CysLTs) LTC4, LTD4 and LTE4, are implicated in a wide variety of inflammatory disorders. These lipid mediators are …
A Stamm, K Reimers, S Strauß, P Vogt, T Scheper… - …, 2016 - degruyter.com
Wound healing is essential for the restoration of the barrier function of the skin. During this process, cells at the wound edges proliferate and migrate, leading to re-epithelialization of …
Simple Summary Glioblastoma multiforme is a brain tumor with a very unfavorable prognosis, where the vast majority of patients do not survive a year after diagnosis. One line …
R He, Y Chen, Q Cai - Pharmacological research, 2020 - Elsevier
Abstract Leukotriene B4 (LTB4) is a major type of lipid mediator that is rapidly generated from arachidonic acid through sequential action of 5-lipoxygenase (5-LO), 5-lipoxygenase …
K Saeki, T Yokomizo - Seminars in immunology, 2017 - Elsevier
Abstract Leukotriene B 4 (LTB 4), a lipid mediator produced from arachidonic acid, is a chemoattractant for inflammatory leukocytes. We identified two receptors for LTB 4, the high …
T Yokomizo - The journal of biochemistry, 2015 - academic.oup.com
Abstract Leukotriene B4 (LTB4) is a potent inflammatory mediator derived from arachidonic acid. Two G protein-coupled receptors for LTB4 have been identified: a high-affinity receptor …
I Ontoria-Oviedo, E Amaro-Prellezo… - International Journal of …, 2022 - mdpi.com
Impaired wound healing in patients with type 2 diabetes (DM2) is characterized by chronic inflammation, which delays wound closure. Specialized pro-resolving lipid mediators …