Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse

H Morton, S Kshirsagar, E Orlov, LE Bunquin… - Free Radical Biology …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

Mitochondrial dysfunction: a potential therapeutic target to treat Alzheimer's disease

SN Rai, C Singh, A Singh, MP Singh, BK Singh - Molecular Neurobiology, 2020 - Springer
Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …

Mitochondrial permeability transition: a pore intertwines brain aging and Alzheimer's disease

K Jia, H Du - Cells, 2021 - mdpi.com
Advanced age is the greatest risk factor for aging-related brain disorders including
Alzheimer's disease (AD). However, the detailed mechanisms that mechanistically link aging …

[HTML][HTML] The role and therapeutic implication of protein tyrosine phosphatases in Alzheimer's disease

X Zhao, L Xiong, L She, L Li, P Huang… - Biomedicine & …, 2022 - Elsevier
Protein tyrosine phosphatases (PTPs) are important regulator of neuronal signal
transduction and a growing number of PTPs have been implicated in Alzheimer's disease …

Impact of chronic conditions and dementia in rural West Texas: a healthy aging study

H Morton, T Basu, C Bose… - Journal of Alzheimer's …, 2022 - content.iospress.com
Alzheimer's disease (AD) is a devastating illness in elderly individuals, that currently has no
known cure. Causal genetic factors only account for 1-2% of AD patients. However, other …

Cordia dichotoma G. Forst fruit prophylactic against Alzheimer's risk factors: in vitro study

FM Ibrahim, AY Ibrahim, HM Amer… - … Lincei. Scienze Fisiche …, 2024 - Springer
Alzheimer's disease (AD) is a neurological ailment that is progressive and incurable.
Enzymes, including acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and …

Lifestyle and risk factors of dementia in rural West Texas

PH Reddy - Journal of Alzheimer's Disease, 2019 - content.iospress.com
In October 2018, the Texas Tech University Health Sciences Center (TTUHSC) held its first
annual Healthy Aging and Dementia Research Symposium. The symposium was conceived …

[PDF][PDF] ISAR Journal of Applied Medical Sciences

PR Kamaljeet - researchgate.net
As an essential regulator of neuronal signal transmission, protein tyrosine phosphatases
(PTPs) have been associated with an emerging variety of neurological diseases, including …