Design of virus-based nanomaterials for medicine, biotechnology, and energy

AM Wen, NF Steinmetz - Chemical Society Reviews, 2016 - pubs.rsc.org
This review provides an overview of recent developments in “chemical virology.” Viruses, as
materials, provide unique nanoscale scaffolds that have relevance in chemical biology and …

Nanoparticle‐based paramagnetic contrast agents for magnetic resonance imaging

J Pellico, CM Ellis, JJ Davis - Contrast media & molecular …, 2019 - Wiley Online Library
Magnetic resonance imaging (MRI) is a noninvasive medical imaging modality that is
routinely used in clinics, providing anatomical information with micron resolution, soft tissue …

Template‐directed synthesis of porous and protective core–shell bionanoparticles

S Li, M Dharmarwardana, RP Welch… - Angewandte Chemie …, 2016 - Wiley Online Library
Metal–organic frameworks (MOFs) are promising high surface area coordination polymers
with tunable pore structures and functionality; however, a lack of good size and …

Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles

P Lam, NF Steinmetz - Biomaterials science, 2019 - pubs.rsc.org
While highly promising in medicine, gene therapy requires delivery agents to protect and
target nucleic acid therapeutics. We developed a plant viral siRNA delivery platform making …

Plant virus-based materials for biomedical applications: Trends and prospects

S Eiben, C Koch, K Altintoprak, A Southan… - Advanced drug delivery …, 2019 - Elsevier
Nanomaterials composed of plant viral components are finding their way into medical
technology and health care, as they offer singular properties. Precisely shaped, tailored …

The pharmacology of plant virus nanoparticles

CI Nkanga, NF Steinmetz - Virology, 2021 - Elsevier
The application of nanoparticles for medical purposes has made enormous strides in
providing new solutions to health problems. The observation that plant virus-based …

Protein corona-enabled systemic delivery and targeting of nanoparticles

D Chen, S Ganesh, W Wang, M Amiji - The AAPS journal, 2020 - Springer
Upon systemic administration, nanoparticles encounter serum proteins in the biological
system resulting in the formation of “protein corona” on the surface. Increased understanding …

Modified TMV particles as beneficial scaffolds to present sensor enzymes

C Koch, K Wabbel, FJ Eber… - Frontiers in plant …, 2015 - frontiersin.org
Tobacco mosaic virus (TMV) is a robust nanotubular nucleoprotein scaffold increasingly
employed for the high density presentation of functional molecules such as peptides …

Serum albumin 'camouflage'of plant virus based nanoparticles prevents their antibody recognition and enhances pharmacokinetics

S Shukla - Biomaterials, 2016 - Elsevier
Plant virus-based nanoparticles (VNPs) are a novel class of nanocarriers with unique
potential for biomedical applications. VNPs have many advantageous properties such as …

Synthesis, modification and bioapplications of nanoscale copper chalcogenides

B Yun, H Zhu, J Yuan, Q Sun, Z Li - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Copper chalcogenides have a simple general formula, variable atomic ratios, and
complicated crystal structures, which lead to their wealth of optical, electrical, and magnetic …